Impact of Transcranial Direct Current Stimulation on Dual-Task Gait Performance in Parkinson's Disease: A Systematic Review.
Background: Parkinson's disease (PD) impairs motor and cognitive functions, increasing fall risk during dual-task activities. While transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, has been studied for improving these functions in PD, its effect on dual-tas...
| Published in: | NeuroRehabilitation Vol. 56; no. 3; pp. 289 - 302 |
|---|---|
| Main Authors: | , , , , |
| Format: | research systematic review tables/charts Journal Article |
| Published: |
Sage Publications Inc.
May2025
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=184909755&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 184909755 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10538135 3RE jtl: NeuroRehabilitation issn: 10538135 maglogo: N pubinfo: dt: May2025 vid: 56 iid: 3 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 184909755 182915983 184909755 184909755 10.1177/10538135241308786 184909755 ppf: 289 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Impact of Transcranial Direct Current Stimulation on Dual-Task Gait Performance in Parkinson's Disease: A Systematic Review. aug: au: Moeyersons, Charlotte Karagiannidou, Evgenia Al Omari, Sarah Swinnen, Eva Firouzi, Mahyar affil: Rehabilitation Research group, Department of Physiotherapy, Human Physiology and Anatomy, Vrije Universiteit Brussel, Brussels, Belgium sug: subj: Parkinson Disease Therapy Transcranial Direct Current Stimulation Evaluation Gait Analysis Task Performance and Analysis Human Systematic Review PubMed Embase Multitasking Behavior Clinical Assessment Tools Quality Assessment Descriptive Statistics Funding Source ab: Background: Parkinson's disease (PD) impairs motor and cognitive functions, increasing fall risk during dual-task activities. While transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique, has been studied for improving these functions in PD, its effect on dual-task gait remains unclear. Objective: This review aims to evaluate the effects of tDCS on dual-task gait performance in PD. Methods: A systematic search was conducted in PubMed, Embase, and Web of Science for studies published before September 2024. Eligible studies included PD patients, used tDCS, and measured dual-task gait performance. Two researchers independently assessed methodological quality using the Cochrane Risk of Bias tool. Results: Four randomized controlled trials and four crossover studies, involving 222 PD patients (mean age 64.17 years, range 50.9–72) at Hoehn & Yahr stages 1–3, met the inclusion criteria. Three of six studies targeting the dorsolateral prefrontal cortex showed significant improvements in dual-task gait performance, particularly in gait speed (p ≤ 0.046), compared to sham. No significant improvements were observed with primary motor cortex or cerebellar stimulation (all p 's ≥ 0.100). Conclusions: tDCS targeting the dorsolateral prefrontal cortex may improve dual-task gait performance in PD, but further studies are needed to refine protocols and confirm its therapeutic potential. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|