Heart Rate Variability as a Possible Biomarker of Cognitive-Motor Integration in Post-Stroke Patients.

Heart Rate Variability (HRV) refers to variation in time intervals between consecutive heartbeats, indicating autonomic nervous system's control over the heart. Time and frequency analysis of HRV could serve as predictors for severity and functional outcome in stroke. Aim of this study is to verify...

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Publicado en:Advances in Rehabilitation Science & Practice pp. 1 - 11
Autores principales: Penati, Rachele, Robustelli, Alessandro, Gasperini, Giulio, Specchia, Alessandro, Paleari, Valeria, Guanziroli, Eleonora, Molteni, Franco
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. 5/5/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 5/5/2025
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        atl: Heart Rate Variability as a Possible Biomarker of Cognitive-Motor Integration in Post-Stroke Patients.
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          Penati, Rachele
          Robustelli, Alessandro
          Gasperini, Giulio
          Specchia, Alessandro
          Paleari, Valeria
          Guanziroli, Eleonora
          Molteni, Franco
        affil: Villa Beretta Rehabilitation Center, Valduce Hospital, Costa Masnaga, Lecco, Italy
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        subj:
          Cognition
          Psychomotor Performance
          Heart Rate Variability
          Biological Markers
          Stroke Patients Psychosocial Factors
          Stroke Rehabilitation
          Task Performance and Analysis Evaluation
          Italy
          Human
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          Descriptive Statistics
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          Analysis of Variance
          Pearson's Correlation Coefficient
          Post Hoc Analysis
          Brain Injuries
          Autonomic Nervous System
          Cognitive Flexibility
          Upper Extremity
          Motor Skills
          Parasympathetic Nervous System
          Hemiplegia
          Ischemic Stroke
          Hemorrhagic Stroke
          Electrocardiography
          Mirror Therapy
          Brain Hemispheres
          Heart Rate
          Middle Aged: 45-64 years
          Aged: 65+ years
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      ab: Heart Rate Variability (HRV) refers to variation in time intervals between consecutive heartbeats, indicating autonomic nervous system's control over the heart. Time and frequency analysis of HRV could serve as predictors for severity and functional outcome in stroke. Aim of this study is to verify if HRV, measured during cognitive and sensorimotor upper limb (UL) tasks, can be used as a biomarker of cognitive-motor interaction in post-stroke patients. Forty-six patients with unilateral brain injury following stroke were enrolled: 27 (58.7%) ischemic, 19 hemorrhagic, 24 (52.2%) subacute (<6 months), and 22 chronic. Mean age at evaluation was 61 years. Right side was affected in 16 subjects (34.8%). Each patient underwent HRV recording in the following conditions: (1) Rest (5 minutes); (2) Visuomotor simulation training of the affected upper limb (UL) using Dessintey IVS3 (DE, 5 minutes); (3) Motor Imagery of the affected UL (MI, 5 minutes). UL functional outcome measures were collected for both affected and less affected sides. All patients showed reduced HRV in time and frequency domains and sympathetic tone predominance at rest. During DE and MI, a significant reduction in time domain was observed. In frequency domains, low frequency decreases during DE, with parasympathetic tone predominance. In the subgroup analyses for lesion side, only right hemiparetic patients showed parasympathetic predominance during mental tasks of the upper limb (DE and MI. No correlation was found between HRV parameters and UL functional scales. Different HRV response in time and frequency domains to mental task was observed between right and left hemiparetic subjects. This could be explained by different anatomical-functional substrates between right and left hemisphere and could reflect different behaviors during UL cognitive-motor tasks. HRV parameters were not correlated with clinical functional assessment scales, likely meaning that they possible exploring different domains.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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