Unveiling the Uncommon: Pyoderma Gangrenosum as an Extraintestinal Complication of Ulcerative Colitis.

Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder characterized by neutrophil accumulation, commonly appearing as erythematous papules or pustules that can coalesce into extensive ulcers. It is the second most common dermatologic manifestation of inflammatory bowel disease, though it af...

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Publicado en:ACG Case Reports Journal Vol. 12; no. 4; pp. 1 - 4
Autores principales: Glover, Caleb, Rida, Ali, Nguyen, Eric, Cay, Edward, Ocasio-Cortes, Gisela, Stefanko, Summer, Fotouhi, Arman, Ross, Albert
Formato: case study pictorial Journal Article
Publicado: American College of Gastroenterology Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
      vid: 12
      iid: 4
      pid: 94678
      pub: American College of Gastroenterology
      place: Bethesda, Maryland
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        atl: Unveiling the Uncommon: Pyoderma Gangrenosum as an Extraintestinal Complication of Ulcerative Colitis.
      aug:
        au:
          Glover, Caleb
          Rida, Ali
          Nguyen, Eric
          Cay, Edward
          Ocasio-Cortes, Gisela
          Stefanko, Summer
          Fotouhi, Arman
          Ross, Albert
        affil: McLaren-Greater Lansing Hospital, Lansing, MI
      sug:
        subj:
          Colitis, Ulcerative Complications
          Colitis, Ulcerative Diagnosis
          Colitis, Ulcerative Symptoms
          Pyoderma Gangrenosum Diagnosis
          Skin Manifestations
          Female
          Aged
          Wounds and Injuries Etiology
          Debridement
          Infliximab Therapeutic Use
          Steroids Therapeutic Use
          Pyoderma Gangrenosum Drug Therapy
          Colitis, Ulcerative Drug Therapy
          Aged: 65+ years
          Female
      ab: Pyoderma gangrenosum (PG) is a rare inflammatory skin disorder characterized by neutrophil accumulation, commonly appearing as erythematous papules or pustules that can coalesce into extensive ulcers. It is the second most common dermatologic manifestation of inflammatory bowel disease, though it affects ,1% of patients with inflammatory bowel disease. We present a case of a 66-year-old woman with a history of hypothyroidism and hypertension who developed nonhealing abdominal wounds following a small pustule. Despite multiple debridements and antibiotics, her condition worsened, alongside a history of bloody diarrhea for 2.5 years. Investigations led to a diagnosis of ulcerative colitis and PG. The patient was treated with high-dose steroids and infliximab. This case highlights the rarity of abdominal PG as an extraintestinal manifestation of ulcerative colitis and emphasizes the importance of early diagnosis and treatment in improving outcomes for affected patients.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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