DFT Investigation of H Activation by [M(NHPnPr)('S3')] (M = Ni, Pd). Insight into Key Factors Relevant to the Design of Hydrogenase Functional Models.

Density functional theory has been used to investigate the reaction between H and [Ni(NHPnPr)-(`S3')] or [Pd(NHPnPr)('S3')], where `S3' = bis(2-sulfanylphenyl)sulfide(2-), which are among the few synthetic complexes featuring a metal coordination environment similar to that observed in the [NiFe] hy...

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Publicado en:Journal of the American Chemical Society Vol. 127; no. 38; pp. 13180 - 13190
Autores principales: Zampella, Giuseppe, Bruschi, Maurizio, Fantucci, Piercarlo, De Gioia, Luca
Formato: Artículo
Publicado: American Chemical Society 9/28/2005
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Acceso en línea:Ver este registro en EBSCOhost
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        atl: DFT Investigation of H Activation by [M(NHPnPr)('S3')] (M = Ni, Pd). Insight into Key Factors Relevant to the Design of Hydrogenase Functional Models.
      aug:
        au:
          Zampella, Giuseppe
          Bruschi, Maurizio
          Fantucci, Piercarlo
          De Gioia, Luca
        affil:
          Department of Biotechnology and Biosciences, University of Milan-Bicocca, Piazza della Scienza 2, I-20156 Milan, Italy.
          Department of Environmental Sciences, University of Milan-Bicocca, Piazza della Scienza 2, I-20156 Milan, Italy.
      su:
        Density functionals
        Functional analysis
        Chemical reactions
        Hydrogenase
        Metathesis reactions
        Catalysts
      sug:
        subj:
          Density functionals
          Functional analysis
          Chemical reactions
          Hydrogenase
          Metathesis reactions
          Catalysts
      ab: Density functional theory has been used to investigate the reaction between H and [Ni(NHPnPr)-(`S3')] or [Pd(NHPnPr)('S3')], where `S3' = bis(2-sulfanylphenyl)sulfide(2-), which are among the few synthetic complexes featuring a metal coordination environment similar to that observed in the [NiFe] hydrogenase active site and capable of catalyzing H heterolytic cleavage. Results allowed us to unravel the reaction mechanism, which is consistent with an oxidative addition—hydrogen migration pathway for [Ni(NHPnPr)('S3')], whereas metathesis is also possible with [Pd(NHPnPr)('S3')]. Unexpectedly, H binding and activation implies structural reorganization of the metal coordination environment. It turns out that the structural rearrangement in [Ni(NHPnPr)('S3')] and [Pd(NHPnPr)('S3')) can take place due to the peculiar structural features of the Ni and Pd ligands, explaining the remarkable catalytic properties. However, the structural reorganization is the most unfavorable step along the H cleavage pathway (ΔG > 100 kJ mol), an observation that is relevant for the design and synthesis of novel biomimetic catalysts.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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