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Potassium Iodide in Dermatology- Recent Advances in Mechanism of Action, Preparation, Uses and Adverse Effects.

Potassium iodide (KI) is a simple yet versatile drug. It has been successfully used for the treatment of various diseases in dermatology, but there are very limited studies on the exact mechanism of action, preparation, and dosage of potassium iodide, causing concerns regarding its toxicity. This ar...

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Publicado en:Indian Journal of Dermatology Vol. 70; no. 3; pp. 169 - 170
Autores principales: Goel, Nishant, Doshi, Bhavana R.
Formato: review tables/charts Journal Article
Publicado: Wolters Kluwer India Pvt Ltd May/Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May/Jun2025
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      pub: Wolters Kluwer India Pvt Ltd
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        atl: Potassium Iodide in Dermatology- Recent Advances in Mechanism of Action, Preparation, Uses and Adverse Effects.
      aug:
        au:
          Goel, Nishant
          Doshi, Bhavana R.
        affil: From the Department of Dermatology, Venereology and Leprosy, J. N. Medical College, Belagavi, Karnataka, India
      sug:
        subj:
          Skin Diseases Drug Therapy
          Potassium Iodide Therapeutic Use
          Potassium Iodide Pharmacodynamics
          Potassium Iodide Adverse Effects
          Drug Compounding
          Potassium Iodide Contraindications
          Cost Benefit Analysis
          Patient Safety
          Drug Efficacy
          Treatment Outcomes
      ab: Potassium iodide (KI) is a simple yet versatile drug. It has been successfully used for the treatment of various diseases in dermatology, but there are very limited studies on the exact mechanism of action, preparation, and dosage of potassium iodide, causing concerns regarding its toxicity. This article reviews the multimodal mechanism of action of KI and standardises the method of preparation of a saturated solution of potassium iodide (SSKI) on an OPD basis. It also lists the existing and newer indications, optimal dosages, adverse effects, and contraindications of potassium iodide, thereby enabling the proper utilisation of this age-old remedy as a cost-effective yet safe treatment option for various inflammatory dermatoses, including panniculitis (erythema nodosum, erythema induratum, subacute nodular migratory panniculitis), Wegener's granulomatosis, granuloma annulare, Behcet's syndrome, pyoderma gangrenosum, Sweet's syndrome, and erythema multiforme. Potassium iodide is also used for fungal infections, including cutaneous and lymphocutaneous sporotrichosis, cutaneous cryptococcosis, entomophthoramycosis, human pythiosis, chromoblastomycosis, and mucormycosis.
      pubtype: Academic Journal
      doctype:
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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