Race/Ethnicity and Other Predictors of Early-Onset Type 2 Diabetes Mellitus in the US Population.
Objectives: Among US adults aged 20 + years in the USA with previously diagnosed type 2 diabetes mellitus (T2DM), we aimed to estimate the prevalence of early-onset T2DM (onset at age < 50.5 years) and to test associations between early-onset T2DM and race/ethnicity, and other hypothesized predictor...
| Publicado en: | Journal of Racial & Ethnic Health Disparities Vol. 12; no. 3; pp. 1482 - 1491 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185098981&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185098981 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 21973792 GQHQ jtl: Journal of Racial & Ethnic Health Disparities issn: 21973792 maglogo: N pubinfo: dt: Jun2025 vid: 12 iid: 3 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 185098981 176163824 185098981 185098981 10.1007/s40615-024-01980-8 185098981 ppf: 1482 ppct: 9 formats: tig: atl: Race/Ethnicity and Other Predictors of Early-Onset Type 2 Diabetes Mellitus in the US Population. aug: au: Fouotsa, Noé Carème Manfouo Ndjaboue, Ruth Ngueta, Gerard affil: https://ror.org/00pthr413 CHU de Sherbrooke Research Center, DOCC (Diabetes, Obesity and Cardiovasvascular Complications), CRCHUS-Hôpital Fleurimont, 12Eme Avenue Nord, 3001, Sherbrooke, Québec, Canada sug: subj: Race Factors Ethnic Groups Diabetes Mellitus, Type 2 Risk Factors Diabetes Mellitus, Type 2 Prevention and Control Diabetes Mellitus, Type 2 Epidemiology Risk Assessment Human Male Female Adult Middle Age Aged Aged, 80 and Over United States Surveys Diabetic Patients Glycated Hemoglobin Analysis Prevalence Machine Learning Algorithms Smoking Marital Status Educational Status Obesity Hypertension Health Personnel Psychosocial Factors Self Report Body Mass Index Reliability and Validity Validation Studies Multivariate Analysis Logistic Regression Questionnaires Descriptive Statistics Comparative Studies Confidence Intervals Odds Ratio Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Objectives: Among US adults aged 20 + years in the USA with previously diagnosed type 2 diabetes mellitus (T2DM), we aimed to estimate the prevalence of early-onset T2DM (onset at age < 50.5 years) and to test associations between early-onset T2DM and race/ethnicity, and other hypothesized predictors. Methods: We pooled data from the annual National Health and Nutrition Examination Surveys (NHANES) over the years 2001 through 2018. We tested hypotheses of association and identified predictors using stepwise logistic regression analysis, and 11 supervised machine learning classification algorithms. Results: After appropriate weighting, we estimated that among adults in the USA aged 20 + years with previously diagnosed T2DM, the prevalence of early-onset was 52.9% (95% confidence intervals, 49.6 to 56.2%). Among Non-Hispanic Whites (NHW) the prevalence was 48.6% (95% CI, 44.6 to 52.6%), among Non-Hispanic Blacks: 56.9% (95% CI, 51.8 to 62.0%), among Hispanics: 62.7% (95% CI, 53.2 to 72.3%). In the final multivariable logistic regression model, the top-3 markers predicting early-onset T2DM in males were NHB ethnicity (OR = 2.97; 95% CI: 2.24–3.95) > tobacco smoking (OR = 2.79; 95% CI: 2.18–3.58) > high education level (OR = 1.65; 95% CI: 1.27–2.14) in males. In females, the ranking was tobacco smoking (OR = 2.59; 95% CI: 1.90–3.53) > Hispanic ethnicity (OR = 1.49; 95% CI: 1.08–2.05) > obesity (OR = 1.30; 95% CI: 0.91–1.86) in females. The acculturation score emerged from the machine learning approach as the dominant marker explaining the race disparity in early-onset T2DM. Conclusions: The prevalence of early-onset T2DM was higher among NHB and Hispanic people, than among NHW people. Independently of race/ethnicity, acculturation, tobacco smoking, education level, marital status, obesity, and hypertension were also predictive. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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