Increased morbidities in pyoderma gangrenosum with extensive surgical debridement in Taiwan: a case series.

Objective: Delayed diagnosis and consequent extensive debridement in cases of pyoderma gangrenosum (PG) may lead to poor wound healing and unfavourable prognosis. We aimed to evaluate the epidemiological and clinical features of PG in Taiwan and investigate the clinical courses of patients who under...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Wound Care Vol. 34; no. 5; pp. 380 - 385
Autores principales: Hou, Yi-Li, Lee, Chih-Hung, Cheng, Yu-Wen
Formato: pictorial research tables/charts Journal Article
Publicado: Mark Allen Holdings Limited May2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185128987&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 185128987
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        09690700
        H3U
      jtl: Journal of Wound Care
      issn: 09690700
      maglogo: N
    pubinfo:
      dt: May2025
      vid: 34
      iid: 5
      pid: 11383
      pub: Mark Allen Holdings Limited
    artinfo:
      ui:
        185128987
        185128987
        185128987
        10.12968/jowc.2022.0041
        185128987
      ppf: 380
      ppct: 5
      formats:
      tig:
        atl: Increased morbidities in pyoderma gangrenosum with extensive surgical debridement in Taiwan: a case series.
      aug:
        au:
          Hou, Yi-Li
          Lee, Chih-Hung
          Cheng, Yu-Wen
        affil: MD, Department of Dermatology, Kaohsiung Chang-Gung Memorial Hospital, Kaohsiung, Taiwan
      sug:
        subj:
          Pyoderma Gangrenosum Epidemiology
          Pyoderma Gangrenosum Symptoms
          Pyoderma Gangrenosum Surgery
          Surgical Debridement Methods
          Disease Attributes
          Morbidity
          Taiwan
          Human
          Male
          Female
          Adult
          Retrospective Design
          Record Review
          Hospitalization
          Surgical Patients
          Descriptive Statistics
          Inflammatory Bowel Diseases
          Sex Factors
          Wound Care
          Wound Healing
          Adrenal Cortex Hormones
          Comorbidity
          Dermatologists
          Adult: 19-44 years
          Male
          Female
      ab: Objective: Delayed diagnosis and consequent extensive debridement in cases of pyoderma gangrenosum (PG) may lead to poor wound healing and unfavourable prognosis. We aimed to evaluate the epidemiological and clinical features of PG in Taiwan and investigate the clinical courses of patients who underwent extensive surgical debridement. Method: In this retrospective study, patients diagnosed with PG at a referral centre in Taiwan between 2001 and 2021 were recruited. The patients were divided into a debrided group and a non-debrided group. Results: The cohort comprised a total of 15 patients, five of whom were in the debrided group and 10 in the non-debrided group. Among all 15 patients, the average age at diagnosis was 40 years with a male preponderance (67%). PG tended to involve multiple sites (73%), the lower limbs (87%), ulcerations (80%) and had a diameter <10cm (93%). Seven patients (47%) had medical comorbidities, including inflammatory bowel disease (20%) and hypertension (20%). Ulcerative manifestations, lack of typical associated comorbidities, delayed diagnosis, prolonged lengths of hospitalisation, and high cumulative doses of systemic corticosteroids were observed in the debrided group. Conclusion: This is the first study to describe the epidemiological and clinical characteristics of PG in Taiwan in English to our knowledge. The results were mostly consistent with the existing literature, except an apparent male preponderance. Moreover, we highlight the importance of accurate diagnosis and avoidance of aggressive surgical debridement in patients with PG for both dermatologist and non-dermatologist.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N