Reduced HLA-I Transcript Levels and Increased Abundance of a CD56 dim NK Cell Signature Are Associated with Improved Survival in Lower-Grade Gliomas.

Simple Summary: Human leukocyte antigen class I (HLA-I) molecules can modulate anti-tumour immune responses from CD8+ T cells and NK cells. However, how deregulated HLA-I expression impacts clinical outcomes in cancer patients has remained unclear. Using computational approaches, we investigated the...

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Publicado en:	Cancers Vol. 17; no. 9; pp. 1570 - 1590
Autores principales:	Khan, Md Abdullah Al Kamran, Peel, Lorenza, Sedgwick, Alexander J., Sun, Yuhan, Vivian, Julian P., Corbett, Alexandra J., Dolcetti, Riccardo, Mantamadiotis, Theo, Barrow, Alexander D.
Formato:	research tables/charts Journal Article
Publicado:	MDPI May2025
Acceso en línea:	Ver este registro en EBSCOhost