Prevalence and Determinants of Viral Suppression in Young People Living with HIV on Antiretroviral Therapy in Southern Africa: A Cross-Sectional Analysis of HIV Survey Data of 2020 and 2021.
Young People Living with HIV (YPLHIV, 15–24 years) are an important demographic of Persons Living with HIV (PLHIV) globally and in Southern Africa. However, YPLHIV experience poor outcomes across the HIV diagnostic and treatment cascade due to multiple factors. We estimated the prevalence and determ...
| Publicado en: | AIDS & Behavior Vol. 29; no. 6; pp. 1962 - 1973 |
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| Autores principales: | , , , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Jun2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185134584&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185134584 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10907165 G1T jtl: AIDS & Behavior issn: 10907165 maglogo: N pubinfo: dt: Jun2025 vid: 29 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 185134584 183404703 185134584 185134584 10.1007/s10461-025-04662-6 185134584 ppf: 1962 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Prevalence and Determinants of Viral Suppression in Young People Living with HIV on Antiretroviral Therapy in Southern Africa: A Cross-Sectional Analysis of HIV Survey Data of 2020 and 2021. aug: au: Msosa, Takondwa Charles Kabaghe, Alinune Twabi, Hussein Hassan Mpinganjira, Samuel Mzumara, Wongani Sumari-De Boer, Marion Aarnoutse, Rob Wit, Tobias Rinke De Chipungu, Geoffrey Ngowi, Kennedy Kalata, Newton Mukoka, Madalo Msefula, Chisomo Swai, Iraseni Zimba, Boston Semphere, Robina Makhumba, Glory Nliwasa, Marriott affil: https://ror.org/04dkp9463 Amsterdam UMC, Department of Global Health, Location University of Amsterdam, Amsterdam, The Netherlands sug: subj: HIV Infections Epidemiology HIV Infections Prevention and Control HIV Infections Prevention and Control Anti-Retroviral Agents Therapeutic Use AIDS Patients Treatment Outcomes Viral Load Funding Source South Africa Human Male Female Adolescence Adult Middle Age Aged Aged, 80 and Over Cross Sectional Studies Confidence Intervals Descriptive Statistics Bivariate Statistics Multivariate Statistics Malawi Mozambique Zimbabwe Lesotho Adolescent: 13-18 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Young People Living with HIV (YPLHIV, 15–24 years) are an important demographic of Persons Living with HIV (PLHIV) globally and in Southern Africa. However, YPLHIV experience poor outcomes across the HIV diagnostic and treatment cascade due to multiple factors. We estimated the prevalence and determinants of HIV viral suppression in YPLHIV on antiretroviral therapy (ART) in selected Southern African countries. We used publicly available data from Malawi, Zimbabwe, Mozambique, Lesotho, and Eswatini collected during the Population-based HIV Impact Assessments (PHIAs) of 2020 to 2021. Weighted proportions, and 95% confidence intervals (CI) were computed to estimate the prevalence of viral suppression (< 1000c/ml) and bivariate and multivariate analyses were conducted to identify determinants of viral suppression. A total of 855 records of YPLHIV on ART were included in the analysis. The prevalence of viral suppression in YPLHIV on ART was 82.4% (95% CI: 76.7, 86.9). Residing in Mozambique and duration on ART were inversely associated with viral suppression; adjusted odds ratios (AORs) of 0.37 (95% CI: 0.14, 0.95), and 0.87 (95% CI: 0.80, 0.94), respectively. A negative result in the depression screen, being married/cohabitating, and ever switching an ART regimen were positively associated with viral suppression: AORs of 5.78 (95% CI: 2.21, 15.11), 3.72 (95% CI: 1.44, 9.63), and 3.44 (95% CI: 1.69, 7), respectively. YPLHIV had suboptimal viral suppression lower than the UNAIDS 95% targets and may benefit from further research and tailored interventions addressing modifiable factors associated with viral suppression such as depression. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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