Impact of Attempted Mode of Delivery on Neonatal Outcomes in Nulliparous Individuals According to Body Mass Index.

Objective: This study aimed to compare neonatal and maternal outcomes based on the attempted mode of delivery, stratified by prepregnancy body mass index (BMI; kg/m 2) in nulliparous individuals. Study Design: This was a repeated cross-sectional analysis of U.S. vital statistics Live Birth and Infan...

Descripción completa

Detalles Bibliográficos
Publicado en:American Journal of Perinatology Vol. 42; no. 8; pp. 1003 - 1012
Autores principales: Atwani, Rula, Saade, George, Kawakita, Tetsuya
Formato: research tables/charts Journal Article
Publicado: Thieme Medical Publishing Inc. Jun2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185256884&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 185256884
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        07351631
        GQK
      jtl: American Journal of Perinatology
      issn: 07351631
      maglogo: N
    pubinfo:
      dt: Jun2025
      vid: 42
      iid: 8
      pid: 2811
      pub: Thieme Medical Publishing Inc.
      place: New York, New York
    artinfo:
      ui:
        185256884
        185256884
        185256884
        10.1055/a-2451-9197
        185256884
      ppf: 1003
      ppct: 9
      formats:
      tig:
        atl: Impact of Attempted Mode of Delivery on Neonatal Outcomes in Nulliparous Individuals According to Body Mass Index.
      aug:
        au:
          Atwani, Rula
          Saade, George
          Kawakita, Tetsuya
        affil: Department of Obstetrics and Gynecology, Macon and Joan Brock Virginia Health Sciences at Old Dominion University (ODU), Norfolk, Virginia
      sug:
        subj:
          Nulliparas Psychosocial Factors
          Delivery, Obstetric Methods
          Prepregnancy Care Methods
          Body Mass Index
          Pregnancy Outcomes Evaluation
          Human
          Female
          Adult
          Expectant Mothers
          Pregnancy
          United States
          Cross Sectional Studies
          Comparative Studies
          Matched-Pair Analysis
          Repeated Measures
          Cesarean Section
          Vaginal Birth
          Reference Values
          Labor
          Perinatal Death
          Maternal Death
          Pregnancy Complications
          Parity
          Infant, Newborn
          Adult: 19-44 years
          Infant, Newborn: birth-1 month
          Female
      ab: Objective: This study aimed to compare neonatal and maternal outcomes based on the attempted mode of delivery, stratified by prepregnancy body mass index (BMI; kg/m 2) in nulliparous individuals. Study Design: This was a repeated cross-sectional analysis of U.S. vital statistics Live Birth and Infant Death-linked data from 2011 to 2020. The analysis was restricted to nulliparas with singleton pregnancies and cephalic presentation who delivered at term. Our primary outcome was a composite neonatal outcome. We also examined a composite maternal outcome. We compared outcomes between individuals who attempted labor and those who opted for nonlabor cesarean delivery, categorized by BMI (<18.5, 18.5–24.9, 25–29.9, 30–39.9, ≥40). To account for significant differences in baseline characteristics between groups, Coarsened Exact Matching was applied using a k-to-k solution. We employed modified Poisson regression and calculated a difference-in-difference (DID) to compare differences in predicted proportions across BMI categories. Results: Out of 9,709,958 individuals, 1,083,332 were included in the matched analysis. Compared with attempted vaginal delivery, nonlabor cesarean delivery was associated with an increased risk of the composite neonatal outcome across all BMI categories. However, the increase in risk was less pronounced in higher BMI categories compared with the reference group (BMI 18.5–24.9). For maternal outcomes, nonlabor cesarean delivery was associated with an increased risk of the composite maternal outcome in the BMI 18.5–24.9 and 25–29.9 categories. In contrast, the risk of adverse maternal outcomes associated with nonlabor cesarean delivery was lower in higher BMI groups compared with the reference group, with DID values ranging from −0.12 in the BMI 30–39.9 group to −0.16 in the BMI ≥40 group. Conclusion: Nonlabor cesarean delivery, as compared with attempted vaginal delivery, was associated with adverse neonatal outcomes across all BMI categories, though the relative increase in risk was diminished in higher BMI groups. Key Points: Compared with attempting vaginal delivery, nonlabor cesarean was associated with an increased risk of the composite neonatal outcome in all BMI classes (range of absolute risk difference 1.27–2.35%). The increased risk of the composite neonatal outcome was less pronounced in nulliparous individuals with a BMI of 40 kg/m 2 or greater. Even for individuals with high BMI, attempting vaginal delivery is reasonable.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N