A Self-Supervised Equivariant Refinement Classification Network for Diabetic Retinopathy Classification.

Diabetic retinopathy (DR) is a retinal disease caused by diabetes. If there is no intervention, it may even lead to blindness. Therefore, the detection of diabetic retinopathy is of great significance for preventing blindness in patients. Most of the existing DR detection methods use supervised meth...

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Publicado en:Journal of Imaging Informatics in Medicine Vol. 38; no. 3; pp. 1796 - 1812
Autores principales: Fan, Jiacheng, Yang, Tiejun, Wang, Heng, Zhang, Huiyao, Zhang, Wenjie, Ji, Mingzhu, Miao, Jianyu
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2025
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        atl: A Self-Supervised Equivariant Refinement Classification Network for Diabetic Retinopathy Classification.
      aug:
        au:
          Fan, Jiacheng
          Yang, Tiejun
          Wang, Heng
          Zhang, Huiyao
          Zhang, Wenjie
          Ji, Mingzhu
          Miao, Jianyu
        affil: https://ror.org/05sbgwt55 School of Information Science and Engineering, Henan University of Technology, 450001, Zhengzhou, China
      sug:
        subj:
          Diabetic Retinopathy Classification
          Self Care
          Deep Learning
          Image Interpretation, Computer Assisted
          Human
          Funding Source
          Blindness Prevention and Control
          Neural Networks (Computer)
          Learning Methods
          Supervisors and Supervision
          Diagnosis, Computer Assisted
          Uncertainty
          Machine Learning
          Algorithms
      ab: Diabetic retinopathy (DR) is a retinal disease caused by diabetes. If there is no intervention, it may even lead to blindness. Therefore, the detection of diabetic retinopathy is of great significance for preventing blindness in patients. Most of the existing DR detection methods use supervised methods, which usually require a large number of accurate pixel-level annotations. To solve this problem, we propose a self-supervised Equivariant Refinement Classification Network (ERCN) for DR classification. First, we use an unsupervised contrast pre-training network to learn a more generalized representation. Secondly, the class activation map (CAM) is refined by self-supervision learning. It first uses a spatial masking method to suppress low-confidence predictions, and then uses the feature similarity between pixels to encourage fine-grained activation to achieve more accurate positioning of the lesion. We propose a hybrid equivariant regularization loss to alleviate the degradation caused by the local minimum in the CAM refinement process. To further improve the classification accuracy, we propose an attention-based multi-instance learning (MIL), which weights each element of the feature map as an instance, which is more effective than the traditional patch-based instance extraction method. We evaluate our method on the EyePACS and DAVIS datasets and achieved 87.4% test accuracy in the EyePACS dataset and 88.7% test accuracy in the DAVIS dataset. It shows that the proposed method achieves better performance in DR detection compared with other state-of-the-art methods in self-supervised DR detection.
      pubtype: Academic Journal
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        pictorial
        research
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      ougenre: Article
    language: English
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