An Adaptive SCG-ECG Multimodal Gating Framework for Cardiac CTA.

Cardiovascular disease (CVD) is the leading cause of death worldwide. Coronary artery disease (CAD), a prevalent form of CVD, is typically assessed using catheter coronary angiography (CCA), an invasive, costly procedure with associated risks. While cardiac computed tomography angiography (CTA) pres...

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Published in:Journal of Imaging Informatics in Medicine Vol. 38; no. 3; pp. 1669 - 1681
Main Authors: Ganesh, Shambavi, Abozeed, Mostafa, Aziz, Usman, Tridandapani, Srini, Bhatti, Pamela T.
Format: equations & formulas research tables/charts tracings Journal Article
Published: Springer Nature Jun2025
Online Access:View this record in EBSCOhost
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      dt: Jun2025
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      pub: Springer Nature
      place: New York, New York
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        atl: An Adaptive SCG-ECG Multimodal Gating Framework for Cardiac CTA.
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          Ganesh, Shambavi
          Abozeed, Mostafa
          Aziz, Usman
          Tridandapani, Srini
          Bhatti, Pamela T.
        affil: https://ror.org/01zkghx44 Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA
      sug:
        subj:
          Computed Tomography Angiography Methods
          Electrocardiography
          Prediction Models
          Blood Pressure Determination
          Diagnosis, Cardiovascular
          Human
          Conceptual Framework
          Neural Networks (Computer)
          Systolic Pressure
          Diastolic Pressure
          Ultrasonography
          Image Processing, Computer Assisted
          Cardiovascular Diseases Diagnosis
          Sensitivity and Specificity
          Regression
          Descriptive Statistics
          Funding Source
      ab: Cardiovascular disease (CVD) is the leading cause of death worldwide. Coronary artery disease (CAD), a prevalent form of CVD, is typically assessed using catheter coronary angiography (CCA), an invasive, costly procedure with associated risks. While cardiac computed tomography angiography (CTA) presents a less invasive alternative, it suffers from limited temporal resolution, often resulting in motion artifacts that degrade diagnostic quality. Traditional ECG-based gating methods for CTA inadequately capture cardiac mechanical motion. To address this, we propose a novel multimodal approach that enhances CTA imaging by predicting cardiac quiescent periods using seismocardiogram (SCG) and ECG data, integrated through a weighted fusion (WF) approach and artificial neural networks (ANNs). We developed a regression-based ANN framework (r-ANN WF) designed to improve prediction accuracy and reduce computational complexity, which was compared with a classification-based framework (c-ANN WF), ECG gating, and US data. Our results demonstrate that the r-ANN WF approach improved overall diastolic and systolic cardiac quiescence prediction accuracy by 52.6% compared to ECG-based predictions, using ultrasound (US) as the ground truth, with an average prediction time of 4.83 ms. Comparative evaluations based on reconstructed CTA images show that both r-ANN WF and c-ANN WF offer diagnostic quality comparable to US-based gating, underscoring their clinical potential. Additionally, the lower computational complexity of r-ANN WF makes it suitable for real-time applications. This approach could enhance CTA's diagnostic quality, offering a more accurate and efficient method for CVD diagnosis and management.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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