Utility of cell population data to detect myelodysplastic neoplasms in routine laboratory analysis.
Myelodysplastic neoplasms (MDN) are a heterogeneous group of clonal disorders characterised by abnormal production and proliferation of cells within the myeloid cell linage. MDN is more commonly diagnosed in older people and the clinical manifestations vary depending on the severity and specific typ...
| Publicado en: | Australian Journal of Medical Science Vol. 46; no. 1; pp. 21 - 31 |
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| Autor principal: | |
| Formato: | pictorial research tables/charts Journal Article |
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Australian Institute of Medical Scientists
Feb2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185313138&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185313138 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10381643 GD50 jtl: Australian Journal of Medical Science issn: 10381643 maglogo: N pubinfo: dt: Feb2025 vid: 46 iid: 1 pid: 88256 pub: Australian Institute of Medical Scientists place: Milton, Queensland, <Blank> artinfo: ui: 185313138 185313138 185313138 185313138 ppf: 21 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Utility of cell population data to detect myelodysplastic neoplasms in routine laboratory analysis. aug: au: Gunson, Hanna affil: Fellowship dissertation Haematology Department, Royal Hobart Hospital, Hobart, Tasmania sug: subj: Myelodysplastic Syndromes Diagnosis Hematologic Neoplasms Diagnosis Cellular Structures Cell Line, Tumor Hematologic Tests Diagnostic Tests, Routine Early Detection of Cancer Human Middle Age Cell Proliferation Myeloid Cells Consensus Disease Progression Leukemia, Myeloid, Acute Descriptive Statistics Middle Aged: 45-64 years ab: Myelodysplastic neoplasms (MDN) are a heterogeneous group of clonal disorders characterised by abnormal production and proliferation of cells within the myeloid cell linage. MDN is more commonly diagnosed in older people and the clinical manifestations vary depending on the severity and specific type of the disorder. The disease is often detected during routine blood film examination, triggered by the laboratory review criteria which should be based on the International Consensus group suggested criteria (Barnes et al 2005). While MDN may be slow to progress, progression to acute myeloid leukaemia occurs in approximately 30% of cases (Bejar and Steensma 2014). Early detection of MDN, through triggers outside the Consensus guidelines, may facilitate timely treatment initiation and improve patient outcomes. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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