Increased Sensitivity to Effort and Perception of Effort in People with Schizophrenia.
Objective Motivational deficits in schizophrenia are proposed to be attributable in part to abnormal effort-cost computations, calculations weighing the costs vs. the benefits of actions. Several reports have shown that people with schizophrenia display a reduced willingness to exert effort for mone...
| Published in: | Schizophrenia Bulletin Vol. 51; no. 3; pp. 696 - 710 |
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| Main Authors: | , , , , , , |
| Format: | equations & formulas pictorial research tables/charts Journal Article |
| Published: |
Oxford University Press / USA
May2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185320578&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185320578 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 05867614 2CZ jtl: Schizophrenia Bulletin issn: 05867614 maglogo: N pubinfo: dt: May2025 vid: 51 iid: 3 pid: 622 pub: Oxford University Press / USA artinfo: ui: 185320578 185320578 185320578 10.1093/schbul/sbae162 185320578 ppf: 696 ppct: 14 formats: tig: atl: Increased Sensitivity to Effort and Perception of Effort in People with Schizophrenia. aug: au: Culbreth, Adam J Chib, Vikram S Riaz, Safa S Manohar, Sanjay G Husain, Masud Waltz, James A Gold, James M affil: Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, School of Medicine, Baltimore, MD 21201, United States sug: subj: Schizophrenia Symptoms Persons with Mental Disorders Exertion Intention Motivation Reward Task Performance and Analysis Decision Making Evaluation Human Male Female Adult Middle Age Interviews Self Report Questionnaires Severity of Disability Funding Source Adult: 19-44 years Middle Aged: 45-64 years Male Female ab: Objective Motivational deficits in schizophrenia are proposed to be attributable in part to abnormal effort-cost computations, calculations weighing the costs vs. the benefits of actions. Several reports have shown that people with schizophrenia display a reduced willingness to exert effort for monetary rewards when compared to controls. The primary goal of the current study was to further characterize reduced willingness to exert effort in schizophrenia by determining whether reduced willingness reflects (1) reduced sensitivity to reward, (2) increased sensitivity to effort, or (3) a combination of both. Design We assessed effort-cost decision-making in 30 controls and 30 people with schizophrenia, using 2 separate experimental tasks. Critically, one paradigm allowed for independent estimation of effects of reward and effort sensitivity on choice behavior. The other task isolated effort sensitivity by measuring effort in the absence of reward. Clinical interviews and self-report questionnaires were administered to people with schizophrenia to determine negative symptom severity. Results Across both tasks, we found evidence for reduced willingness to exert effort in people with schizophrenia compared to controls. Further, in both paradigms reduced willingness to exert effort was driven by increased sensitivity to effort in people with schizophrenia compared to controls. In contrast, measures of reward sensitivity did not significantly differ between groups. Surprisingly, we did not find correlations between task variables and measures of negative symptom severity. Conclusions and Relevance These findings further specify prior work by identifying a specific contributory role for increased effort sensitivity in effort-cost decision-making deficits in schizophrenia. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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