Data-driven ascertainment of the symptom profile of pediatric myalgic encephalomyelitis and chronic fatigue syndrome.
Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are characterized by symptoms, such as fatigue, post-exertional malaise, sleep disruption and cognitive impairment. ME and CFS affect individuals across the lifespan; however, the majority of ME and CFS research has focused on adults....
| Publicado en: | International Journal of Child & Adolescent Health Vol. 17; no. 2; pp. 151 - 164 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Nova Science Publishers, Inc.
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185373185&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185373185 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19395930 903I jtl: International Journal of Child & Adolescent Health issn: 19395930 maglogo: N pubinfo: dt: 2024 vid: 17 iid: 2 pid: 1040 pub: Nova Science Publishers, Inc. place: Hauppauge, New York artinfo: ui: 185373185 185373185 185373185 185373185 ppf: 151 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Data-driven ascertainment of the symptom profile of pediatric myalgic encephalomyelitis and chronic fatigue syndrome. aug: au: Sunnquist, Madison Jason, Leonard A. affil: Center for Community Research, DePaul University, Chicago, Illinois, USA sug: subj: Fatigue Syndrome, Chronic Symptoms Encephalitis Symptoms Structural Equation Modeling Encephalitis Diagnosis Fatigue Syndrome, Chronic Diagnosis Human Funding Source Male Female Child Adolescence Epidemiological Research Questionnaires Health Screening Convenience Sample Descriptive Statistics Data Analysis Software Chi Square Test Fatigue Dizziness Bivariate Statistics Exertion Sleep Disorders Cognition Abdominal Pain Child: 6-12 years Adolescent: 13-18 years Male Female ab: Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are characterized by symptoms, such as fatigue, post-exertional malaise, sleep disruption and cognitive impairment. ME and CFS affect individuals across the lifespan; however, the majority of ME and CFS research has focused on adults. Research suggests that the symptom profile of pediatric ME and CFS differs from that of adults, although symptom prevalence estimates vary widely by study due to differences in recruitment methodology, symptom assessment, and application of diagnostic criteria. While two pediatric-specific ME and CFS case definitions exist, pediatricians report continued uncertainty about how to diagnose and treat the condition, often resulting in misdiagnosis and delaying access to appropriate care. Diagnostic variability also contributes to heterogeneity in research samples, hindering the search for biological markers and effective treatments. The current study sought to elucidate the characteristic symptom profile of pediatric ME and CFS through conducting a latent class analysis on symptom data aggregated from over ten thousand children and adolescents. An eight-class solution was extracted, and one class captured the majority of participants with ME and CFS. Individuals in this class endorsed a number of symptoms, including post-exertional malaise, fatigue, sleep problems, and cognitive issues. Additionally, abdominal pain and dizziness were frequently experienced by members of this class, while rarely endorsed by members of other classes. These findings have implications for the development of pediatric-specific case definitions for ME and CFS. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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