The Role of Algorithms in Molecular Tumour Boards—Managing the Gap Between Research and Clinic in Precision Medicine.

The article explores the role of algorithmic procedures in the implementation of the programme of precision medicine (PM), currently pursued in molecular tumour boards (MTBs) that emerged from the confluence of previous tumour boards and the increasing molecularisation of medicine. Our observation o...

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Publicado en:Sociology of Health & Illness Vol. 47; no. 4; pp. 1 - 12
Autores principales: Hofmann, Dominik, Esposito, Elena
Formato: Artículo
Publicado: Wiley-Blackwell May2025
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2025
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      pub: Wiley-Blackwell
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        10.1111/1467-9566.70040
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        atl: The Role of Algorithms in Molecular Tumour Boards—Managing the Gap Between Research and Clinic in Precision Medicine.
      aug:
        au:
          Hofmann, Dominik
          Esposito, Elena
        affil:
          Faculty of Sociology, Bielefeld University, Bielefeld, Germany
          Department of Political and Social Sciences, University of Bologna, Bologna, Italy
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        Italy
        Germany
        Medical technology
        Interprofessional relations
        Diffusion of innovations
        Empirical research
        Interviewing
        Medical informatics
        Research funding
        Database management
        Scientific observation
        Decision making in clinical medicine
        Translational research
        Workflow
        Tumors
        Individualized medicine
        Algorithms
        Health care teams
        Webinars
      sug:
        subj:
          Medical technology
          Interprofessional relations
          Diffusion of innovations
          Empirical research
          Interviewing
          Italy
          Germany
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          Medical, Dental, and Hospital Equipment and Supplies Merchant Wholesalers
          Surgical and Medical Instrument Manufacturing
          Surgical Appliance and Supplies Manufacturing
          Medical informatics
          Research funding
          Database management
          Scientific observation
          Decision making in clinical medicine
          Translational research
          Workflow
          Tumors
          Individualized medicine
          Algorithms
          Health care teams
          Webinars
      keyword:
        algorithms
        molecular tumour boards
        molecularization
        precision medicine
        translational medicine
        algorithms
        molecular tumour boards
        molecularization
        precision medicine
        translational medicine
      ab: The article explores the role of algorithmic procedures in the implementation of the programme of precision medicine (PM), currently pursued in molecular tumour boards (MTBs) that emerged from the confluence of previous tumour boards and the increasing molecularisation of medicine. Our observation of the deliberations in MTBs, confirmed by interviews with participants, shows that the crucial contribution of algorithms in all stages of the processing of molecular data is neither acknowledged nor mentioned. One reason, we argue, is that these highly innovative technologies are very distant from the traditional skills and training of clinicians. The mediation through MTBs provides algorithmic procedures with the viability required to be implemented in medical decisions—and is more effective the more it goes unnoticed. Contrary to the widespread assumption of a blurring boundary between research and care, we claim that the intensification of contacts and exchanges among research endeavours and clinical operations makes the separation between the two fields increasingly sharp. As a consequence, there is a need for new forms of translation, which are accomplished by MTBs.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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