Around the EQUATOR With Clin‐STAR: AI‐Based Randomized Controlled Trial Challenges and Opportunities in Aging Research.

The CONSORT 2010 statement is a guideline that provides an evidence‐based checklist of minimum reporting standards for randomized trials. With the rapid growth of Artificial Intelligence (AI) based interventions in the past 10 years, the CONSORT‐AI extension was created in 2020 to provide guidelines...

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Published in:Journal of the American Geriatrics Society Vol. 73; no. 5; pp. 1365 - 1376
Main Authors: Yang, Betsy, Park, Caroline, Lin, Steven, Muralidharan, Vijaytha, Kado, Deborah M.
Format: Article
Published: Wiley-Blackwell May2025
Subjects:
Online Access:View this record in EBSCOhost
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      dt: May2025
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      pub: Wiley-Blackwell
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        185399586
        10.1111/jgs.19362
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        atl: Around the EQUATOR With Clin‐STAR: AI‐Based Randomized Controlled Trial Challenges and Opportunities in Aging Research.
      aug:
        au:
          Yang, Betsy
          Park, Caroline
          Lin, Steven
          Muralidharan, Vijaytha
          Kado, Deborah M.
        affil:
          Section of Geriatric Medicine, Division of Primary Care and Population Health, Department of Medicine, Stanford School of Medicine, Palo Alto California,, USA
          Geriatric Research Education Research and Clinical Center (GRECC), Veterans Administration Healthcare System, Palo Alto California,, USA
          Stanford Healthcare AI Applied Research Team (HEA3RT), Stanford School of Medicine, Palo Alto California,, USA
          Department of Family Medicine, USC Keck School of Medicine, Pasadena California,, USA
          Division of Primary Care and Population Health, Department of Medicine, Stanford School of Medicine, Palo Alto California,, USA
          Department of Dermatology, Aneurin Bevan NHS Health Trust, Newport, UK
      su:
        Elder care
        Artificial intelligence
        Mindfulness
        Patient-centered care
        Health equity
        Clinical decision support systems
        Digital health
        Polypharmacy
        Movement disorders
      sug:
        subj:
          Elder care
          Artificial intelligence
          Mindfulness
          Patient-centered care
          Health equity
          Continuing Care Retirement Communities
          Clinical decision support systems
          Digital health
          Polypharmacy
          Movement disorders
      ab: The CONSORT 2010 statement is a guideline that provides an evidence‐based checklist of minimum reporting standards for randomized trials. With the rapid growth of Artificial Intelligence (AI) based interventions in the past 10 years, the CONSORT‐AI extension was created in 2020 to provide guidelines for AI‐based randomized controlled trials (RCT). The Clin‐STAR "Around the EQUATOR" series features existing reported standards while also highlighting the inherent complexities of research involving research of older participants. In this work, we propose that when designing AI‐based RCTs involving older adults, researchers adopt a conceptual framework (CONSORT‐AI‐5Ms) designed around the 5Ms (Mind, Mobility, Medications, Matters most, and Multi‐complexity) of Age‐Friendly Healthcare Systems. Employing the 5Ms in this context, we provide a detailed rationale and include specific examples of challenges and potential solutions to maximize the impact and value of AI RCTs in an older adult population. By combining the original intent of CONSORT‐AI with the 5Ms framework, CONSORT‐AI‐5Ms provides a patient‐centered and equitable perspective to consider when designing AI‐based RCTs to address the diverse needs and challenges associated with geriatric care.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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