Development of an Innovative Pipeline With Fusion, Digital Planning, and Three‐Dimensional Printing to Improve Mitral Valve Interventional Care.

Aim: Transesophageal echocardiography (TEE) is the modality of choice for mitral valve (MV) interventional planning. However, computed tomography (CT) has been proposed as a standard screening tool for MV interventions to assess the risk of injury to the left circumflex artery. We aimed to develop a...

Descripción completa

Detalles Bibliográficos
Publicado en:Echocardiography Vol. 42; no. 5; pp. 1 - 8
Autores principales: Man, Jelle P., Bouma, Berto J., Asselbergs, Folkert, Chamuleau, Steven A. J., Schuuring, Mark J.
Formato: diagnostic images research tables/charts Journal Article
Publicado: Wiley-Blackwell May2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185414292&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 185414292
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        07422822
        GSE
      jtl: Echocardiography
      issn: 07422822
      maglogo: Y
    pubinfo:
      dt: May2025
      vid: 42
      iid: 5
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
    artinfo:
      ui:
        185414292
        185414292
        185414292
        10.1111/echo.70184
        185414292
      ppf: 1
      ppct: 7
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: C
          – @attributes:
              type: P
      tig:
        atl: Development of an Innovative Pipeline With Fusion, Digital Planning, and Three‐Dimensional Printing to Improve Mitral Valve Interventional Care.
      aug:
        au:
          Man, Jelle P.
          Bouma, Berto J.
          Asselbergs, Folkert
          Chamuleau, Steven A. J.
          Schuuring, Mark J.
        affil: Department of Cardiology, Amsterdam UMC, Heart Center, Amsterdam, the Netherlands
      sug:
        subj:
          Printing, Three-Dimensional
          Mitral Valve Diseases Therapy
          Mitral Valve Diseases Surgery
          Digital Technology
          Quality Improvement
          Tomography, X-Ray Computed
          Health Personnel
          Individualized Medicine
          Heart Valve Prosthesis
          Human
          Funding Source
          Echocardiography, Transesophageal
          Usability Study
          Risk Assessment
          Algorithms
          Mitral Valve Anatomy and Histology
          Mitral Valve Insufficiency Therapy
          Cardiologists
      ab: Aim: Transesophageal echocardiography (TEE) is the modality of choice for mitral valve (MV) interventional planning. However, computed tomography (CT) has been proposed as a standard screening tool for MV interventions to assess the risk of injury to the left circumflex artery. We aimed to develop a pipeline to fuse CT and MV modalities and create three‐dimensional (3D) printable models of the MV apparatus to enhance interventional planning and assessed its usability among clinicians. Methods and Results: The design, production, and assessment of the 3D‐printed personalized models were based on TEE enriched with data from CT. The digital pipeline consisted of fusion with a mutual information algorithm using 3D Slicer (Slicer) and Elastix toolboxes. Flexible 3D printing was performed using Agilus 30 Clear. The pipeline was feasible for achieving semiautomatic fusion of anatomical structures related to MV interventional planning. Visualization of fused synergistic information for 3D planning could be provided in three distinct cases of MV regurgitation (secondary MR with tenting, flail leaflet, and prolapse). The 3D printing resulted in a flexibility in line with actual tissue allowing for tactile modification. An average System Usability Score of 71 indicates a moderately good usability among imaging cardiologists, intervention cardiologists, and cardiac surgeons. Conclusion: The presented pipeline with digital planning and personalized 3D printing has reached the technology readiness level for application in mitral valve interventions, and prospective clinical trials with endpoints of surgical effectiveness. Comprehensive and efficient interactions between clinicians and technical staff are essential to establish well‐designed patient‐specific interventions.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N