Cancer Symptom Clusters in Children and Adolescents with Cancer Undergoing Chemotherapy: A Systematic Review.

Objective: To synthesize and analyze the prevalence, composition, longitudinal stability, and predictors of cancer symptom clusters in children and adolescents undergoing chemotherapy. Method: A systematic literature review was conducted in accordance with the PRISMA 2020 guidelines. Evidence was so...

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Publicado en:Nursing Reports Vol. 15; no. 5; pp. 163 - 181
Autores principales: Lopes-Júnior, Luís Carlos, Grassi, Jonathan, Freitas, Marcela Bortoleto, Trigo, Fernanda Ercília Souza, Jardim, Fabrine Aguilar, Nunes, Karolini Zuqui, Vasconcelos, Karla Anacleto de, Lima, Regina Aparecida Garcia de
Formato: research systematic review tables/charts Journal Article
Publicado: MDPI May2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2025
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        atl: Cancer Symptom Clusters in Children and Adolescents with Cancer Undergoing Chemotherapy: A Systematic Review.
      aug:
        au:
          Lopes-Júnior, Luís Carlos
          Grassi, Jonathan
          Freitas, Marcela Bortoleto
          Trigo, Fernanda Ercília Souza
          Jardim, Fabrine Aguilar
          Nunes, Karolini Zuqui
          Vasconcelos, Karla Anacleto de
          Lima, Regina Aparecida Garcia de
        affil: Graduate Program in Nutrition and Health, Health Sciences Center at the Federal University of Espírito Santo (UFES), Vitória 29040-091, ES, Brazil
      sug:
        subj:
          Childhood Neoplasms Epidemiology
          Childhood Neoplasms Drug Therapy
          Childhood Neoplasms Symptoms
          Human
          Child
          Adolescence
          Systematic Review
          Medline
          PubMed
          Cochrane Library
          Embase
          Psycinfo
          Gray Literature
          Checklists
          Antineoplastic Agents
          Oncology Nursing
          Fatigue
          Sleep Disorders
          Self Concept
          Childhood Neoplasms Psychosocial Factors
          Quality Assessment
          Descriptive Statistics
          Funding Source
          Child: 6-12 years
          Adolescent: 13-18 years
      ab: Objective: To synthesize and analyze the prevalence, composition, longitudinal stability, and predictors of cancer symptom clusters in children and adolescents undergoing chemotherapy. Method: A systematic literature review was conducted in accordance with the PRISMA 2020 guidelines. Evidence was sourced from MEDLINE/PubMed, Cochrane Library, Embase, PsycINFO, and Web of Science, as well as clinical trial registries (Clinical Trials WHO-ICTRP) and gray literature. The search was performed in February 2025, with no restrictions on publication date or language. Two independent reviewers screened and selected the studies. The methodological quality of the included studies was assessed using design-specific tools, and the findings were synthesized narratively. Results: A total of 6221 records were identified, with 12 studies meeting the inclusion criteria. These studies were published between 2010 and 2024 in the United States, Brazil, China, and Turkey. Cancer symptom clusters in children and adolescents followed well-defined patterns, with the gastrointestinal, emotional, fatigue-related, somatic, and self-image clusters being the most prevalent. Conclusions: Early identification of these cancer symptom clusters is essential for guiding interprofessional teams in delivering personalized, evidence-based care to children and adolescents with cancer and their families.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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