Investigating the antimicrobial and anti-adhesion properties of the alcoholic extract of Verbascum sinuatum plant on the biofilm formation of three intestinal bacteria.
Introduction: Intestinal bacteria enter the body through contaminated food and water or contact with infected people and animals. These bacteria cause blood, urine, bone or nervous system infections in humans. The most important bacteria that cause these diseases include Salmonella typhimurium, Kleb...
| Published in: | International Journal of Travel Medicine & Global Health Vol. 13; no. 1; pp. 24 - 33 |
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| Main Authors: | , |
| Format: | pictorial research Journal Article |
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Tarbiat Modares University Press
Mar2025
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185517075&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185517075 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 23221100 FUA0 jtl: International Journal of Travel Medicine & Global Health issn: 23221100 maglogo: N pubinfo: dt: Mar2025 vid: 13 iid: 1 pid: 93586 pub: Tarbiat Modares University Press artinfo: ui: 185517075 185517075 185517075 10.30491/ijtmgh.2024.482328.1437 185517075 ppf: 24 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Investigating the antimicrobial and anti-adhesion properties of the alcoholic extract of Verbascum sinuatum plant on the biofilm formation of three intestinal bacteria. aug: au: Siahi, Fatemeh Seyed Bonab, Zahra Hojjati affil: Department of Microbiology, Bonab Branch, Islamic Azad University, Bonab, Iran sug: subj: Salmonella Infections Drug Therapy Klebsiella Infections Drug Therapy Dysentery, Bacillary Drug Therapy Plant Extracts Therapeutic Use Antiinfective Agents Therapeutic Use Biofilms Drug Effects Human Plant Extracts Pharmacodynamics Descriptive Statistics Drug Resistance, Microbial ab: Introduction: Intestinal bacteria enter the body through contaminated food and water or contact with infected people and animals. These bacteria cause blood, urine, bone or nervous system infections in humans. The most important bacteria that cause these diseases include Salmonella typhimurium, Klebsiella pneumoniae and Shigella sonnei. The increasing drug resistance of bacteria created the necessity of investigating the antibacterial effects of Verbascum sinuatum plant extract on the planktonic form and biofilm of all three bacteria in question. Methods: After preparing and cultivating standard bacteria and preparing biofilm from three intestinal bacteria, the effect of alcoholic extract of V.sinuatum on planktonic bacteria and the biofilm caused by them was investigated by well plate method. The value of minimum inhibitory concentration (MIC) and minimum bacteriocidal concenteration (MBC) was determined on planktonic form and biofilm of bacteria. Results: results showed that the alcoholic extract of V.sinuatum has antimicrobial effect on Salmonella typhimurium and Klebsiella pneumoniae. V.sinuatum also has inhibitory effect and has antimicrobial effect on the biofilm of Salmonella typhimurium and Klebsiella pneumoniae. Conclusion: The formation of biofilm is an important factor in stability and as a result, it is the cause of infections that are difficult to deal with. Klebsiella pneumoniae and Salmonella typhimurium also have the ability to form biofilm and it is considered an important cause of many infections, so it is important to fight this infectious factor using the extract of V.sinuatum plant. pubtype: Academic Journal doctype: pictorial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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