Risk Prediction Models of Subsyndromal Delirium in Critically Ill Patients: A Systematic Review and Meta‐Analysis.

Background: The number of predictive models for assessing the risk of subsyndromal delirium (SSD) in critically ill patients is increasing, yet the quality and applicability of these models in clinical practice remain unclear. Aim: To systematically review and critically evaluate the existing risk p...

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Publicado en:Nursing in Critical Care Vol. 30; no. 3; pp. 1 - 14
Autores principales: Wu, Fei, Wang, Tong, Xing, Yana, Cai, Weixin, Zhang, Ran
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell May2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2025
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/nicc.70063
        185589238
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        atl: Risk Prediction Models of Subsyndromal Delirium in Critically Ill Patients: A Systematic Review and Meta‐Analysis.
      aug:
        au:
          Wu, Fei
          Wang, Tong
          Xing, Yana
          Cai, Weixin
          Zhang, Ran
        affil: Nursing Department, Beijing TianTan Hospital, Capital Medical University, Beijing, China
      sug:
        subj:
          Delirium Diagnosis
          Delirium Epidemiology
          Critical Illness
          Intensive Care Units
          Risk Assessment
          Critical Care
          Predictive Value of Tests
          Human
          Critically Ill Patients Psychosocial Factors
          Prediction Models
          Artificial Intelligence
          Decision Support Systems, Clinical
          China
          Japan
          PubMed
          Embase
          Clinical Assessment Tools
          Descriptive Statistics
          Data Analysis Software
          Confidence Intervals
          Systematic Review
          Meta Analysis
          Funding Source
      ab: Background: The number of predictive models for assessing the risk of subsyndromal delirium (SSD) in critically ill patients is increasing, yet the quality and applicability of these models in clinical practice remain unclear. Aim: To systematically review and critically evaluate the existing risk prediction models. Study Design: Eleven Chinese and English databases, including PubMed, Web of Science and Embase, were searched from their inception to August 16, 2024. Two researchers independently screened the literature, extracted data and assessed the risk of bias and applicability using the prediction model risk of bias assessment tool. Meta‐analysis was conducted using Stata 17.0. Results: Eight studies were included. The SSD incidence in ICU patients ranged from 8.97% to 34.5%. The most commonly used predictors were the APACHE II score and age. The reported area under the curve (AUC) ranged from 0.788 to 0.923, with the pooled AUC value for the five validated models being 0.87 (95% CI: 0.82–0.92). Six studies had a high risk of bias, while two had an unclear risk. Conclusions: The eight included models demonstrated good performance in early identification and screening of high‐risk critically ill patients for SSD, but they all exhibited a high risk of bias regarding model quality. Relevance to Clinical Practice: ICU professionals should carefully select and validate existing models based on their specific clinical settings before applying them. Alternatively, they can conduct new models incorporating multimodal data and artificial intelligence algorithms, utilizing large sample sizes, robust research designs and multi‐center external validation.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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