Identifying hazardous alcohol use in primary care using phosphatidylethanol: Timing of screening matters.
Background and Aims: Alcohol is a well‐established risk factor for numerous health conditions, making screening for hazardous alcohol use in healthcare a critical task. While self‐reported data suggest that alcohol consumption varies across seasons, this seasonal fluctuation has not yet been confirm...
| Publicado en: | Addiction Vol. 120; no. 7; pp. 1441 - 1450 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185619491&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185619491 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Jul2025 vid: 120 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 185619491 183624563 185619491 185619491 10.1111/add.70036 185619491 ppf: 1441 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Identifying hazardous alcohol use in primary care using phosphatidylethanol: Timing of screening matters. aug: au: Månsson, Viktor Hårdstedt, Maria Hammarberg, Anders Hake, Anders LoMartire, Riccardo affil: Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden sug: subj: Time Factors Primary Health Care Phospholipids Blood Biological Markers Blood Alcohol Drinking Substance Use Disorders Diagnosis Human Nonexperimental Studies Cross Sectional Studies Medical Records Sweden Descriptive Statistics Substance Use Disorders Epidemiology Logistic Regression Clinical Assessment Tools Sex Factors Male Female Seasons Hematologic Tests Funding Source Male Female ab: Background and Aims: Alcohol is a well‐established risk factor for numerous health conditions, making screening for hazardous alcohol use in healthcare a critical task. While self‐reported data suggest that alcohol consumption varies across seasons, this seasonal fluctuation has not yet been confirmed using objective biological markers. This study aimed to measure whether phosphatidylethanol (PEth) captures variations in hazardous alcohol use across two temporal resolutions: month of the year and day of the week. Design: Observational cross‐sectional study based on data from medical records. Setting: Healthcare services, Region Dalarna, Sweden, between 2017 and 2023. Participants/Cases: Adult patients (n = 62 431, 50% females) screened for hazardous alcohol use with PEth within primary care. Measurements This study utilizes test results from PEth, with results >0.30 μmol/l defined as hazardous alcohol use. We compared the prevalence of hazardous alcohol use across months and weekdays using logistic regression while adjusting for sex, age, smoking status, the Charlson Comorbidity Index and psychiatric diagnoses. Findings The prevalence of hazardous alcohol use increased between May and August, ranging from 13.2% to 15.9%, compared with 10.7% in November. This corresponds to a 48% relative increase in the peak month of July [prevalence ratio (PR) = 1.48, 95% confidence interval (CI) = 1.33–1.64]. Hazardous alcohol use was also more prevalent among patients tested on Mondays (13.0%) compared with Thursdays, with the lowest prevalence (12.0%). The difference was particularly pronounced among female patients, with a 14.0% higher relative prevalence on Mondays (PR = 1.14, 95% CI = 1.02–1.27). Conclusions: In Sweden, the prevalence of hazardous alcohol use appears to fluctuate seasonally and, to a lesser extent, across weekdays, as measured by blood tests for phosphatidylethanol, a biomarker for hazardous alcohol use. November showed the lowest prevalence and July the highest, consistent across age, sex and the year of the observational period. Hazardous alcohol use showed a slight elevation of prevalence during Mondays compared with Tuesday to Friday. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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