Simplifying Management of Cholestasis: A Proposal for a Classification System.
Given the stillbirth risk associated with intrahepatic cholestasis of pregnancy, management to reduce this adverse outcome has primarily involved planned delivery as early as 36 weeks gestation. While earlier planned delivery has decreased the incidence of stillbirth in this population, recently, th...
| Publicado en: | American Journal of Perinatology Vol. 42; no. 9; pp. 1229 - 1235 |
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| Autores principales: | , , , |
| Formato: | algorithm review tables/charts Journal Article |
| Publicado: |
Thieme Medical Publishing Inc.
Jul2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185690057&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185690057 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07351631 GQK jtl: American Journal of Perinatology issn: 07351631 maglogo: N pubinfo: dt: Jul2025 vid: 42 iid: 9 pid: 2811 pub: Thieme Medical Publishing Inc. place: New York, New York artinfo: ui: 185690057 185690057 185690057 10.1055/a-2495-3553 185690057 ppf: 1229 ppct: 6 formats: tig: atl: Simplifying Management of Cholestasis: A Proposal for a Classification System. aug: au: Sarker, Minhazur Ramos, Gladys A. Ferrara, Lauren Gyamfi-Bannerman, Cynthia affil: Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, California sug: subj: Cholestasis, Intrahepatic Complications Cholestasis, Intrahepatic Therapy Pregnancy Complications Risk Factors Risk Assessment Pregnancy Female Practice Guidelines Algorithms Female ab: Given the stillbirth risk associated with intrahepatic cholestasis of pregnancy, management to reduce this adverse outcome has primarily involved planned delivery as early as 36 weeks gestation. While earlier planned delivery has decreased the incidence of stillbirth in this population, recently, there have been multiple published retrospective studies to better correlate the association of adverse outcomes with cholestasis severity. Despite these new data, the uptake of individualized management for cholestasis has been varied from provider to provider. In this opinion, we briefly review the current literature and evidence regarding cholestasis and adverse outcomes and propose a cholestasis classification system with subsequent algorithms for management. Key Points: Recently, multiple studies have further characterized adverse outcomes with cholestasis. Incorporation of severity-associated management into clinical practice is variable. A cholestasis classification system will simplify and streamline management. pubtype: Academic Journal doctype: algorithm review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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