Impact of smoking on diabetes complications: a secondary analysis of the Korean National Health Insurance Service-health screening cohort (2002- 2019).

Purpose: This study aimed to examine the effects of smoking on the incidence of macrovascular and microvascular complications in patients with type 2 diabetes. Methods: We analyzed 35,804 patients diagnosed with type 2 diabetes between 2004 and 2017 using the Korean National Health Insurance Service...

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Publicado en:Journal of Korean Academy of Nursing Vol. 55; no. 2; pp. 222 - 236
Autores principales: Seonmi Yeom, Youngran Yang
Formato: research tables/charts Journal Article
Publicado: Korean Society of Nursing Science May2025
Acceso en línea:Ver este registro en EBSCOhost
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        20053673
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      dt: May2025
      vid: 55
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        atl: Impact of smoking on diabetes complications: a secondary analysis of the Korean National Health Insurance Service-health screening cohort (2002- 2019).
      aug:
        au:
          Seonmi Yeom
          Youngran Yang
        affil: Research Institute of Nursing Science, College of Nursing, Jeonbuk National University, Jeonju, Korea
      sug:
        subj:
          Vascular Diseases Epidemiology
          Vascular Diseases Complications
          Vascular Diseases Risk Factors
          Diabetes Mellitus, Type 2 Complications
          Smoking Complications
          Risk Assessment
          Insurance, Health South Korea
          Health Screening
          Smoking Cessation
          South Korea
          Funding Source
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Secondary Analysis
          Survival Analysis
          Cox Proportional Hazards Model
          Diabetic Neuropathies
          Diabetic Nephropathies
          Diabetic Retinopathy
          Chi Square Test
          Sex Factors
          Age Factors
          Comorbidity
          Physical Activity
          Confidence Intervals
          Data Analysis Software
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Purpose: This study aimed to examine the effects of smoking on the incidence of macrovascular and microvascular complications in patients with type 2 diabetes. Methods: We analyzed 35,804 patients diagnosed with type 2 diabetes between 2004 and 2017 using the Korean National Health Insurance Service-National Health Screening Cohort (2002-2019). Smoking status was categorized into never, former, and current smokers, with further classification based on duration of smoking and daily smoking amount. We conducted survival analysis using a Cox proportional hazards model. Results: Both former and current smokers had significantly elevated risks of macrovascular complications compared to non-smokers, with hazard ratios (HRs) of 1.60 (95% confidence interval [CI], 1.49- 1.66) and 1.10 (95% CI, 1.08-1.17), respectively. Long-term smokers (over 30 years) had significantly higher risks of both macrovascular (HR, 1.35; 95% CI, 1.29-1.42) and microvascular complications (HR, 1.36; 95% CI, 1.30-1.42). Heavy smokers (over 2 packs/day) had a higher risk of developing macrovascular (HR, 1.46; 95% CI, 1.30-1.64) and microvascular (HR, 1.78; 95% CI, 1.60-1.98) complications than never smokers. Notably, former smokers had increased risks of developing neuropathy (HR, 1.40; 95% CI, 1.31-1.49), nephropathy (HR, 1.27; 95% CI, 1.16-1.39), and retinopathy (HR, 1.49; 95% CI, 1.39-1.60). Conclusion: Patients with type 2 diabetes and a history of smoking are at higher risk of developing macrovascular and microvascular complications. Smoking cessation, along with reducing smoking duration and amount, is crucial for lowering these risks.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: Korean
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