Acrylamide exposure, sex hormones, and pubertal status in Japanese adolescents.
Acrylamide may affect sex hormone levels and the timing of sexual maturation. The present study cross-sectionally examined interrelationship between the urinary metabolite of acrylamide exposure, serum sex hormone levels, and pubertal status in 408 Japanese adolescents aged 13–14 years. Their caregi...
| Publicado en: | International Journal of Environmental Health Research Vol. 35; no. 6; pp. 1674 - 1684 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jun2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185725624&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185725624 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Jun2025 vid: 35 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 185725624 179660696 185725624 185725624 10.1080/09603123.2024.2401578 185725624 ppf: 1674 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Acrylamide exposure, sex hormones, and pubertal status in Japanese adolescents. aug: au: Nagata, Chisato Wada, Keiko Yamakawa, Michiyo Sugino, Masaaki Mori, Tomoka Ueyama, Jun Sumoto, Yoshio affil: Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, Gifu, Japan sug: subj: Environmental Exposure Adverse Effects Acrylamides Adverse Effects Metabolites Acrylamides Urine Sex Hormones Blood Puberty Adolescent Development Japan Human Male Female Adolescence Cross Sectional Studies Descriptive Statistics Scales Questionnaires Adolescent Health Sex Factors Testosterone Blood Funding Source Sex Maturation Health Status Adolescent: 13-18 years Male Female ab: Acrylamide may affect sex hormone levels and the timing of sexual maturation. The present study cross-sectionally examined interrelationship between the urinary metabolite of acrylamide exposure, serum sex hormone levels, and pubertal status in 408 Japanese adolescents aged 13–14 years. Their caregivers completed a questionnaire concerning the health status of their children, including pubertal maturation, and the lifestyles of children and parents. Pubertal status was queried by the Pubertal Development Scale. A major metabolite of acrylamide, N-acetyl-S-(2-carbamoylethyl)-cysteine (AAMA) in first-void urine samples. In male students, urinary AAMA was significantly inversely associated with testosterone, puberty stage, and facial hair growth after controlling for covariates. Serum testosterone and DHEAS were significantly positively associated with puberty stage. In female students, urinary AAMA was not associated with puberty stage, the indices, or any measured hormones. The data suggest that exposure to acrylamide may impact the pubertal development of boys through the effects on testosterone level. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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