Right-Hemispheric White Matter Organization Is Associated With Speech Timing in Autistic Children.
Purpose: Converging research suggests that speech timing, including altered rate and pausing when speaking, can distinguish autistic individuals from nonautistic peers. Although speech timing can impact effective social communication, it remains unclear what mechanisms underlie individual difference...
| Published in: | Journal of Speech, Language & Hearing Research Vol. 68; no. 6; pp. 2685 - 2700 |
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| Main Authors: | , , , , , , , |
| Format: | Article |
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American Speech-Language-Hearing Association
Jun2025
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| Subjects: | |
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=185830422&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 185830422 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Jun2025 vid: 68 iid: 6 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 185830422 10.1044/2025_JSLHR-24-00548 ppf: 2685 ppct: 15 formats: fmt: @attributes: type: P size: 3.5MB tig: atl: Right-Hemispheric White Matter Organization Is Associated With Speech Timing in Autistic Children. aug: au: Davison, Kelsey E. Liu, Talia Belisle, Rebecca M. Perrachione, Tyler K. Qi, Zhenghan Gabrieli, John D. E. Tager-Flusberg, Helen Zuk, Jennifer affil: Department of Speech, Language, and Hearing Sciences, Boston University, MA su: Diagnosis of autism Speech Autism Sound recordings Intelligence tests Children Research funding Neural pathways Magnetic resonance imaging Natural language processing Verbal behavior testing Descriptive statistics White matter (Nerve tissue) Asperger's syndrome Neuroradiology Data analysis software Articulation (Speech) sug: subj: Diagnosis of autism Speech Autism Sound recordings Intelligence tests Children Diagnostic Imaging Centers Integrated Record Production/Distribution Sound recording merchant wholesalers Record Production Research funding Neural pathways Magnetic resonance imaging Natural language processing Verbal behavior testing Descriptive statistics White matter (Nerve tissue) Asperger's syndrome Neuroradiology Data analysis software Articulation (Speech) ab: Purpose: Converging research suggests that speech timing, including altered rate and pausing when speaking, can distinguish autistic individuals from nonautistic peers. Although speech timing can impact effective social communication, it remains unclear what mechanisms underlie individual differences in speech timing in autism. Method: The present study examined the organization of speech- and language-related neural pathways in relation to speech timing in autistic and nonautistic children (24 autistic children, 24 nonautistic children [ages: 5--17 years]). Audio recordings from a naturalistic language sampling task (via narrative generation) were transcribed to extract speech timing features (speech rate, pause duration). White matter organization (as indicated by fractional anisotropy [FA]) was estimated for key tracts bilaterally (arcuate fasciculus, superior longitudinal fasciculus [SLF], inferior longitudinal fasciculus [ILF], frontal aslant tract [FAT]). Results: Results indicate associations between speech timing and righthemispheric white matter organization (FA in the right ILF and FAT) were specific to autistic children and not observed among nonautistic controls. Among nonautistic children, associations with speech timing were specific to the left hemisphere (FA in the left SLF). Conclusion: Overall, these findings enhance understanding of the neural architecture influencing speech timing in autistic children and, thus, carry implications for understanding potential neural mechanisms underlying speech timing differences in autism. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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