SHAP-Driven Feature Analysis Approach for Epileptic Seizure Prediction.

Predicting epileptic seizures presents a substantial difficulty in healthcare, with considerable implications for enhancing patient outcomes and quality of life. This paper presents an explainable artificial intelligence (AI) that integrates a one-dimensional convolutional neural network (1D-CNN) wi...

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Published in:Journal of Medical Systems Vol. 49; no. 1; pp. 1 - 18
Main Authors: Hasan, Mohsin, Wu, Wenjuan, Zhao, Xufeng
Format: equations & formulas research tables/charts Journal Article
Published: Springer Nature 6/10/2025
Online Access:View this record in EBSCOhost
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      dt: 6/10/2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-025-02211-1
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        atl: SHAP-Driven Feature Analysis Approach for Epileptic Seizure Prediction.
      aug:
        au:
          Hasan, Mohsin
          Wu, Wenjuan
          Zhao, Xufeng
        affil: https://ror.org/01scyh794 College of Economics and Management, Nanjing University of Aeronautics and Astronautics, Jiangning, 210016, Nanjing, Jiangsu, China
      sug:
        subj:
          Seizures Diagnosis
          Epilepsy Diagnosis
          Electroencephalography Methods
          Artificial Intelligence Utilization
          Human
          Prediction Models
          Convolutional Neural Networks
          Signal Processing, Computer Assisted
          Descriptive Statistics
      ab: Predicting epileptic seizures presents a substantial difficulty in healthcare, with considerable implications for enhancing patient outcomes and quality of life. This paper presents an explainable artificial intelligence (AI) that integrates a one-dimensional convolutional neural network (1D-CNN) with SHapley Additive exPlanations (SHAP). The approach facilitates precise and interpretable seizure prediction utilising electroencephalography (EEG) inputs. The suggested 1D-CNN model with SHAP attains superior performance, exhibiting an accuracy of 98.14% and an F1-score of 98.30% with feature-level explainability and high clinical insight using the CHB-MIT dataset. Through the computation and aggregation of SHAP values across time, we identified the most significant EEG channels, specifically "P7-O1" and "P3-O1", as essential for seizure detection. This transparency is crucial for building practitioners' trust and acceptance of the use of artificial intelligence-based solutions in the clinical domain. The technique can readily operate within portable EEG structures and hospital monitoring systems, triggering real-time alerts to patients. The outcome provides a timely intervention that could include anything from medication adjustments to responses in emergencies, preventing potential injury and improving safety. So, SHAP not only explains the model's predictions, but it also check and improve how much it relies on certain features, which makes it more reliable. Additionally, SHAP's interpretability aids physicians in understanding why the model arrived at its conclusions, increasing trust in the predictions and encouraging its extensive utilisation in diagnostic processes.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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