Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations.

This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The study is a randomised controlled trial in which 28 cerebellar patients aged 7–25 yo were randomly allocated...

Descripción completa

Detalles Bibliográficos
Publicado en:Journal of Autism & Developmental Disorders Vol. 55; no. 7; pp. 2463 - 2480
Autores principales: Butti, Niccolò, Biffi, Emilia, Romaniello, Romina, Finisguerra, Alessandra, Valente, Enza Maria, Strazzer, Sandra, Borgatti, Renato, Urgesi, Cosimo
Formato: pictorial research tables/charts randomized controlled trial Journal Article
Publicado: Springer Nature Jul2025
Acceso en línea:Ver este registro en EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185941318&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 185941318
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        01623257
        AUT
      jtl: Journal of Autism & Developmental Disorders
      issn: 01623257
      maglogo: N
    pubinfo:
      dt: Jul2025
      vid: 55
      iid: 7
      pid: 237
      pub: Springer Nature
      place: New York, New York
    artinfo:
      ui:
        185941318
        176983467
        185941318
        185941318
        10.1007/s10803-024-06349-8
        185941318
      ppf: 2463
      ppct: 17
      formats:
        fmt:
          – @attributes:
              type: T
          – @attributes:
              type: P
      tig:
        atl: Feasibility and Efficacy of a Virtual Reality Social Prediction Training in Children and Young Adults with Congenital Cerebellar Malformations.
      aug:
        au:
          Butti, Niccolò
          Biffi, Emilia
          Romaniello, Romina
          Finisguerra, Alessandra
          Valente, Enza Maria
          Strazzer, Sandra
          Borgatti, Renato
          Urgesi, Cosimo
        affil: https://ror.org/05ynr3m75 Scientific Institute, IRCCS E. Medea, Bosisio Parini, Lecco, Italy
      sug:
        subj:
          Cerebellum Abnormalities
          Cerebellum Abnormalities
          Cerebellar Diseases Rehabilitation
          Virtual Reality
          Social Behavior
          Treatment Outcomes
          Human
          Funding Source
          Male
          Female
          Child
          Adolescence
          Adult
          Randomized Controlled Trials
          Random Assignment
          Motor Skills Disorders Rehabilitation
          Avatars
          Intention
          Games
          Neuropsychological Tests
          Comparative Studies
          Cognition Disorders
          Abnormalities
          Mental Disorders Diagnosed in Childhood
          Theory of Mind
          Social Perception
          Child: 6-12 years
          Adolescent: 13-18 years
          Adult: 19-44 years
          Male
          Female
      ab: This study tested the feasibility and efficacy of a Virtual Reality (VR) social prediction training (VR-Spirit) specifically designed for patients with congenital cerebellar malformation. The study is a randomised controlled trial in which 28 cerebellar patients aged 7–25 yo were randomly allocated to the VR-Spirit or to a control intervention in VR. The VR-Spirit required participants to compete with different avatars in scenarios that prompted them to form predictions about avatars' intentions. The control intervention consisted of games currently adopted for motor rehabilitation. Social prediction as well as secondary neuropsychological and behavioural outcomes were assessed at the beginning (T0), at the end (T2) and after 2 months (T3). The experimental group showed a significant increase, compared to the control participants, in social prediction assessed through a VR task. Moreover, at least at T3, the VR-Spirit enhanced the use of contextual predictions in a computer-based action prediction task. Importantly, these effects were generalized to secondary neuropsychological outcomes, specifically theory of mind and, only at T2, inhibition. No differences between the interventions were detected on emotional-behavioural problems. Lastly, both interventions showed high feasibility and acceptability. These findings confirm that it is possible to develop condition-specific rehabilitative training on the basis of neurocognitive functions impaired in case of congenital malformation. The VR-Spirit demonstrated to generalize its effects to theory of mind abilities, and it might be thus extended to other neurodevelopmental disorders that present social perception deficits and alterations of predictive processing. Trial registration: ISRCTN, ID: ISRCTN22332873. Retrospectively registered on 12 March 2018.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N