Effects of spirulina supplementation on body composition in adults: a GRADE-assessed and dose–response meta-analysis of RCTs.
Background and Aim: Weight management remains a global health concern, with increasing interest in nutritional interventions to support healthy body composition. In recent years, the potential role of supplements like Spirulina has gained considerable attention as a possible intervention. This meta-...
| Publicado en: | Nutrition & Metabolism Vol. 22; no. 1; pp. 1 - 16 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | equations & formulas research tables/charts Journal Article |
| Publicado: |
BioMed Central
6/17/2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=185990801&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 185990801 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 17437075 1CYX jtl: Nutrition & Metabolism issn: 17437075 maglogo: N pubinfo: dt: 6/17/2025 vid: 22 iid: 1 pid: 24147 pub: BioMed Central artinfo: ui: 185990801 185990801 185990801 10.1186/s12986-025-00959-4 185990801 ppf: 1 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Effects of spirulina supplementation on body composition in adults: a GRADE-assessed and dose–response meta-analysis of RCTs. aug: au: Lak, Mohammadyasin Karimi, Mehdi Akhgarjand, Camellia Ghotboddin Mohammadi, Shirin Pam, Pedram Ashtary-Larky, Damoon Pirzad, Samira Amirkhan-Dehkordi, Mohammadreza Shahrbaf, Mohammad Amin Henselmans, Menno Asbaghi, Omid affil: Department of Exercise Physiology, Sport Sciences Research Institute, Tehran, Iran sug: subj: Dietary Supplementation Methods Bacteria Body Composition In Adulthood Dietary Supplements Dose-Response Relationship Treatment Outcomes Human Adult Meta Analysis PubMed Descriptive Statistics Confidence Intervals Adult: 19-44 years ab: Background and Aim: Weight management remains a global health concern, with increasing interest in nutritional interventions to support healthy body composition. In recent years, the potential role of supplements like Spirulina has gained considerable attention as a possible intervention. This meta-analysis aims to evaluate the effectiveness of Spirulina supplementation on body composition in adults. Methods: A comprehensive search strategy was conducted across online databases to find relevant RCTs from inception until December 2024. The primary endpoints were changes in anthropometric indices. Meta-analysis and meta-regression were performed using STATA software, and sensitivity, subgroup, and publication bias analyses were also conducted. Results: The pooled analysis of 17 RCTs indicated that Spirulina supplementation significantly reduced body weight (BW) (WMD: -1.07 kg; p = 0.004), body mass index (BMI) (WMD: -0.40; p = 0.025), body fat percentage (BFP) (WMD: -0.84%; p = 0.002), but had no significant effects on waist circumference (WC) (WMD: -0.46 cm; p = 0.280). Based on Egger's regression test, there is no publication bias for BW (p = 0.097), BMI (p = 0.382), BFP (p = 0.945), and WC (p = 0.488). A significant dose–response effect on BMI and intervention dose (Coefficient: -0.17, P = 0.007) and duration (Coefficient: 0.13, p = 0.042). Conclusion: Spirulina supplementation effectively reduces BW, BMI, and BFP, with stronger effects at higher doses and longer durations, especially in obese or older individuals. While no significant change in WC was observed overall, subgroup analyses suggest potential benefits for specific populations, emphasizing the importance of personalized supplementation strategies. pubtype: Academic Journal doctype: equations & formulas meta analysis research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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