Adverse birth outcomes and associated factors among Sub-Saharan African grand multiparas: a systematic review and meta-analysis.

Background: Adverse birth outcomes associated with grand multiparity are more ambiguous than those linked to multiparity. The primary literature on this issue reveals inconsistent findings across various studies. A paucity of data is evident in systematic reviews and meta-analyses that assess advers...

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Publicado en:Therapeutic Advances in Reproductive Health pp. 1 - 16
Autores principales: Zeleke, Agerie Mengistie, Takele, Getnet Azanaw, Gonete, Yosef Aragaw, Ferede, Yeshiwas Ayale, Tassew, Worku Chekol
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Sage Publications Inc. 6/20/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 6/20/2025
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        atl: Adverse birth outcomes and associated factors among Sub-Saharan African grand multiparas: a systematic review and meta-analysis.
      aug:
        au:
          Zeleke, Agerie Mengistie
          Takele, Getnet Azanaw
          Gonete, Yosef Aragaw
          Ferede, Yeshiwas Ayale
          Tassew, Worku Chekol
        affil: Conceptualization, Department of Midwifery, Debark University College of Health Science, Debark Town, Gondar 790, Ethiopia
      sug:
        subj:
          Multiparas Psychosocial Factors
          Sub-Saharan Africans Psychosocial Factors
          Pregnancy Outcomes Evaluation
          Maternal Health Services
          Human
          Sub-Saharan Africans
          Systematic Review
          Meta Analysis
          PubMed
          Medline
          Pregnancy
          Confidence Intervals
          Female
          Checklists
          Odds Ratio
          Rural Population
          Residence Characteristics
          Pregnancy Complications
          Home Childbirth
          Prenatal Care
          Female
      ab: Background: Adverse birth outcomes associated with grand multiparity are more ambiguous than those linked to multiparity. The primary literature on this issue reveals inconsistent findings across various studies. A paucity of data is evident in systematic reviews and meta-analyses that assess adverse birth outcomes specifically for African grand multiparas. Objectives: To address the pooled adverse birth outcomes and their associated factors among African grand multiparas. Design: Systematic review and meta-analysis. Data sources and methods: Studies were systematically searched from April 20, 2024, to June 15, 2024, using Scopus, Web of Science, PubMed, Science Direct, African Journal Online, and the Wiley Online Library. The Joanna Briggs Institute tool was used for a quality assessment of each primary study. Data were extracted using Excel and analyzed with Stata 11 software. A random-effects model was employed to calculate the pooled estimates. The paper employs appropriate statistical techniques to assess publication bias and heterogeneity, such as the symmetry of the funnel plot, Egger's test, and Cochran's Q test. The study addresses a critical public health issue in Africa, contributing valuable data that could inform policy and healthcare practices aimed at reducing adverse birth outcomes among grand multiparas. A subgroup analysis was performed based on the publication years. Results: The pooled prevalence of adverse birth outcomes among African grand multiparas was 24.97%; 95% CI: 19.97–31.99. Pregnancy-related complications (AOR: 3.17; 95% CI: 2.35–4.28), a history of home births (AOR: 3.30; 95% CI: 1.70–6.40), and rural residence (AOR: 4.12; 95% CI: 3.12–5.44) were significantly associated with adverse birth outcomes among African grand multiparas. Conclusion: Overall, the pooled prevalence of adverse birth outcomes among grand multiparas was comparably high. Variables such as rural residence, previous pregnancy-related complications, and a history of home births were significantly associated with adverse birth outcomes. Strengthening institutional births, providing high-quality prenatal care, and early pregnancy follow-ups are recommended to reduce adverse birth outcomes in grand multiparous women. In addition, improving the availability of comprehensive contraceptive options for rural-residing African grand multiparous women is essential. PROSPERO registration: CRD42024569768.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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