Added diagnostic performance of diffusion-weighted imaging for differentiating malignant from benign gallbladder lesions: a systematic review with meta-analysis.
Background: Gallbladder malignancies, especially gallbladder cancer, are aggressive lesions with a poor prognosis, and correct differentiation from benign lesions is crucial for improved outcomes. Recently, diffusion-weighted imaging (DWI) has demonstrated potential for this aim to evaluate suspicio...
| Publicado en: | Abdominal Radiology Vol. 50; no. 7; pp. 2892 - 2906 |
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| Autores principales: | , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jul2025
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=186105109&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 186105109 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jul2025 vid: 50 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 186105109 181697885 10.1007/s00261-024-04757-z 186105109 ppf: 2892 ppct: 14 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Added diagnostic performance of diffusion-weighted imaging for differentiating malignant from benign gallbladder lesions: a systematic review with meta-analysis. aug: au: Mohebbi, Alisa Mohammadzadeh, Saeed Kiani, Iman Mohammadi, Afshin Tavangar, Seyed Mohammad affil: https://ror.org/01c4pz451 Tehran University of Medical Sciences, Tehran, Iran, Islamic Republic of sug: ab: Background: Gallbladder malignancies, especially gallbladder cancer, are aggressive lesions with a poor prognosis, and correct differentiation from benign lesions is crucial for improved outcomes. Recently, diffusion-weighted imaging (DWI) has demonstrated potential for this aim to evaluate suspicious lesions detected by initial imaging (e.g., ultrasound). Material and methods: The protocol of this review was pre-registered at (https://osf.io/ury4k) PubMed, Web of Science, Embase, and Cochrane Library were searched. The performance of both qualitative (i.e., visual) and quantitative (i.e., apparent diffusion coefficient (ADC)) DWIs was assessed for visualized suspicious lesions detected on preliminary imaging. The added value of combining DWI with conventional magnetic resonance imaging (MRI) for this purpose was also evaluated. Results: After the screening, 27 studies were included. Qualitative analysis showed an area under curve (AUC) of 0.93 (95% confidence interval (CI) = 0.90 to 0.95), while AUC of quantitative analysis was 0.91 (95% CI = 0.89 to 0.94). Adding DWI to conventional MRI protocol added significant values of + 11.27% (95% CI = 0.78% to 21.76%) to sensitivity and + 9.64% (95% CI = 3.90% to 15.39%) to specificity for suspicious lesions on preliminary imaging. Conclusion: DWI offers an accurate, noninvasive method for differentiating benign gallbladder lesions from malignant ones after preliminary imaging. While adding the DWI protocol to conventional MRI imaging does not require technical resources, it significantly improves performance. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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