Mid-to-long term outcomes following renal artery angioplasty in children and young adults with renal artery stenosis: a retrospective review.
Background: This study investigates the efficacy of renal artery angioplasty for pediatric renovascular hypertension (RVH) and describes the role of pre-procedural diagnostic imaging. Methods: Clinical data of patients who underwent angioplasty for RVH from July 2014–May 2023 at a single, tertiary-c...
| Publicado en: | Pediatric Nephrology Vol. 40; no. 8; pp. 2589 - 2598 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=186136028&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 186136028 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0931041X EF1 jtl: Pediatric Nephrology issn: 0931041X maglogo: N pubinfo: dt: Aug2025 vid: 40 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 186136028 184121569 186136028 186136028 10.1007/s00467-025-06727-z 186136028 ppf: 2589 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Mid-to-long term outcomes following renal artery angioplasty in children and young adults with renal artery stenosis: a retrospective review. aug: au: Youssef, Salma Gill, Anne E. Shah, Jay H. Kennedy, Sabina S. Riar, Sandeep K. Hawkins, C. Matthew affil: https://ror.org/05m7pjf47 University College Dublin School of Medicine, Belfield, Dublin, Ireland sug: subj: Renal Artery Obstruction Surgery Renal Artery Obstruction Surgery Renal Artery Obstruction Surgery Hypertension, Renovascular Surgery Angioplasty Treatment Outcomes Human Retrospective Design Infant Child, Preschool Child Adolescence Young Adult Descriptive Statistics Angioplasty, Balloon Postoperative Complications Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adolescent: 13-18 years ab: Background: This study investigates the efficacy of renal artery angioplasty for pediatric renovascular hypertension (RVH) and describes the role of pre-procedural diagnostic imaging. Methods: Clinical data of patients who underwent angioplasty for RVH from July 2014–May 2023 at a single, tertiary-care children's hospital were retrospectively analyzed. Renal angiography was performed in 74 children, mean age: 10.6 years (range, 3mos–20y). Mean follow-up: 2.5 years (range, 4d–10.4y). 45 angioplasty procedures were performed on 28 patients. Results: 11(39.3%) were cured (normotensive, no anti-hypertensive medications), 10(35.7%) were improved (improved BP, decreased anti-hypertensive dose or number of meds), and 7(25%) failed (no improvement) following 1st angioplasty. Of the 17 patients who improved/failed, 12 had a 2nd angioplasty procedure. Of those, 3(25%) were treated with cutting-balloons. 2(16.7%) were cured, 8(66.7%) improved, and 2(16.7%) failed. 5 patients underwent a 3rd angioplasty procedure. 4(80%) were treated with cutting-balloons. 3 (60%) of the 5 patients were cured, 2 (40%) improved. In all, 16/28(57.1%) of patients were cured, and 12/28(42.9%) improved. 19 patients with abnormal angiography had normal CTA(10), MRA(3), and US(17). 14 patients with normal angiography had abnormal CTA(4), MRA(2), and US(13). Major complication rate was 8.9%(4/45) and included renal artery stent with residual in-stent stenosis, arterial extravasation following cutting-balloon angioplasty, arterial dissection, and vasospasm, partially resolved with nitroglycerin/TPA. Conclusions: Angioplasty is an efficacious treatment for pediatric RVH, but may require more than one procedure to achieve successful clinical results. Angiography should be pursued when RVH is suspected, as other imaging modalities are commonly discordant with angiography. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|