A nomogram for predicting non-suicide self-injury in youth depression patients: a longitudinal analysis.

Non-suicidal self-injury (NSSI) behavior is a common issue in youth with depression while lacks a prognostic prediction model. This study aims to develop a nomogram for NSSI in youth with depression. A total of 701 patients were included in the analysis based a youth depression cohort. They were fur...

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Publicado en:European Child & Adolescent Psychiatry Vol. 34; no. 6; pp. 1959 - 1969
Autores principales: Li, Yingwen, Ma, Yarong, Sun, Bin, Rosenheck, Robert, Zhang, Jie, He, Hongbo
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2025
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00787-024-02603-7
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      ppf: 1959
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        atl: A nomogram for predicting non-suicide self-injury in youth depression patients: a longitudinal analysis.
      aug:
        au:
          Li, Yingwen
          Ma, Yarong
          Sun, Bin
          Rosenheck, Robert
          Zhang, Jie
          He, Hongbo
        affil: https://ror.org/00zat6v61 The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China
      sug:
        subj:
          Depression Complications
          Depression Complications
          Self-Injurious Behavior Risk Factors
          Prediction Models
          Risk Assessment
          Human
          Male
          Female
          Adolescence
          Young Adult
          Prospective Studies
          Logistic Regression
          Models, Statistical
          ROC Curve
          Age Factors
          Academic Performance
          Stress, Psychological
          Anxiety
          Confidence Intervals
          Checklists
          Scales
          Mann-Whitney U Test
          Statistical Significance
          Data Analysis Software
          Descriptive Statistics
          Funding Source
          Adolescent: 13-18 years
          Male
          Female
      ab: Non-suicidal self-injury (NSSI) behavior is a common issue in youth with depression while lacks a prognostic prediction model. This study aims to develop a nomogram for NSSI in youth with depression. A total of 701 patients were included in the analysis based a youth depression cohort. They were further divided into a training set and a validation set. The Lasso regression and binary logistic regression were used to select variables for the nomogram. The nomogram's discrimination, calibration, accuracy, clinical applicability, and generalization involved the use of metrics such as the area under the receiver operating characteristic curve (ROC), Hosmer–Lemeshow (HL) test, Brier score, calibration curve, decision curve analysis (DCA), and internal validation. The Delong test was employed to compare the ROC performance between the two models. These patients had an average age of 19.3+/-3.3 years, and 101 (20.6%) individuals reported NSSI. Five risk factors for NSSI were identified: age, age at first medication, previous instances of NSSI, academic stress score in the Adolescent Self-rating Life Events Check List (ASLEC), and somatic anxiety of the 14 item Hamilton Anxiety Rating Scale (HAMA-14). The training set and validation set of binary logistic regression-based model showed good discrimination (area under the curve (AUC) 0.781, 95% CI: 0.735 ~ 0.827; and 0.757, 95% CI: 0.682 ~ 0.831, respectively), calibration (P = 0.421 and 0.175, respectively), and accuracy (Brier score 0.119 to 0.155 and 0.109 to 0.168, respectively). A prognostic nomogram was developed and validated to assist clinicians in predicting NSSI of youth with depression.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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