Methylation Status of the Telomerase Reverse Transcriptase Promoter in Parotid Tumours and Adjacent Parotid Gland Tissue: A Pilot Study on the Implications for Recurrence and Development of Malignancy.

Background/Objectives: The methylation of the hypermethylated oncological region (THOR) of human telomerase reverse transcriptase (hTERT) may forecast tumour aggressiveness. This pilot study aimed to evaluate THOR methylation as a potential biomarker for recurrence/malignant transformation in saliva...

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Publicado en:Current Oncology Vol. 32; no. 6; pp. 312 - 326
Autores principales: Paiva-Correia, António, Apolónio, Joana, Nadal, Alfons, Brandão, José Ricardo, Silva, Nádia, Machado, Bianca, Archilla, Ivan, Castelo-Branco, Pedro, Hellquist, Henrik
Formato: Journal Article
Publicado: MDPI Jun2025
Acceso en línea:Ver este registro en EBSCOhost