Delirium Among Critically Ill Patients With Stroke: Prevalence, Severity, and Outcomes.

Background: Delirium is a common complication of critical illness, but the epidemiology of delirium among stroke patients with critical illness is uncertain. Objectives: To assess the prevalence, severity, and short-term outcomes of delirium in adults admitted to a neurocritical care unit with acute...

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Publicado en:American Journal of Critical Care Vol. 34; no. 4; pp. 266 - 274
Autores principales: Lawson, Thomas N., Tan, Alai, McNett, Molly, Balas, Michele C., Brinda, Amy, Brummel, Nathan E., Happ, Mary B., Tate, Judith A.
Formato: CEU research Journal Article
Publicado: American Association of Critical-Care Nurses Jul2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2025
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      pub: American Association of Critical-Care Nurses
      place: Alisa Veijo, California
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        atl: Delirium Among Critically Ill Patients With Stroke: Prevalence, Severity, and Outcomes.
      aug:
        au:
          Lawson, Thomas N.
          Tan, Alai
          McNett, Molly
          Balas, Michele C.
          Brinda, Amy
          Brummel, Nathan E.
          Happ, Mary B.
          Tate, Judith A.
        affil: lead advanced practice provider, Neurocritical Care Unit, The Ohio State University Wexner Medical Center, The Ohio State University College of Nursing, Columbus
      sug:
        subj:
          Stroke Patients
          Critically Ill Patients
          Delirium Epidemiology
          Delirium Pathology
          Severity of Disability Evaluation
          Delirium Therapy
          Treatment Outcomes Evaluation
          Critical Care
          Intensive Care Units, Neonatal
          Human
          Prospective Studies
          Nonexperimental Studies
          Academic Medical Centers
          United States
          Male
          Female
          Aged
          Prevalence
          Ischemic Stroke
          Cerebral Hemorrhage
          Hemorrhagic Stroke
          Subarachnoid Hemorrhage
          Cerebral Aneurysm
          Clinical Assessment Tools
          Ventilators, Mechanical
          Treatment Duration
          Confidence Intervals
          Length of Stay
          Odds Ratio
          Scales
          Descriptive Statistics
          Education, Continuing (Credit)
          Delirium Diagnosis
          Delirium Prevention and Control
          Hospital Mortality
          Delirium Mortality
          Linear Regression
          Logistic Regression
          Univariate Statistics
          Funding Source
          Aged: 65+ years
          Male
          Female
      ab: Background: Delirium is a common complication of critical illness, but the epidemiology of delirium among stroke patients with critical illness is uncertain. Objectives: To assess the prevalence, severity, and short-term outcomes of delirium in adults admitted to a neurocritical care unit with acute ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoid hemorrhage. Methods: A prospective, observational cohort study was conducted in a neurocritical care unit in the United States. Patients were enrolled within 48 hours of stroke symptom onset. Delirium was assessed daily until study day 7 (or until transfer out of the neurocritical care unit) with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the CAM-ICU-7 delirium severity score. Results: Overall, 44.4% of patients in the cohort had delirium. Prevalence was higher among patients with intracerebral hemorrhage (38%, 60%, and 32% in patients with acute ischemic stroke, intracerebral hemorrhage, and aneurysmal subarachnoid hemorrhage, respectively). Mean CAM-ICU-7 score for patients who had delirium was 5.64. Regression analyses showed patients with delirium had more ventilator days (point estimate, 2.59; 95% CI, 0.73-4.44), longer ICU and hospital lengths of stay (point estimates, 3.33 [95% CI, 1.36-5.31] and 6.76 [3.43-10.09], respectively), lower odds of discharge home (odds ratio, 0.42; 95% CI, 0.19-0.94), and higher odds of worse modified Rankin score of 3 or higher at discharge (odds ratio, 2.58; 95% CI, 1.04-6.36). Higher delirium severity resulted in worse outcomes. Conclusions: Delirium is common among critically ill stroke patients, especially those with intracerebral hemorrhage, and patients who experience delirium have worse outcomes. Increasing severity of delirium is associated with adverse outcomes.
      pubtype: Academic Journal
      doctype:
        CEU
        research
        Journal Article
      ougenre: Article
    language: English
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