ImmunoPET imaging of Trop2 expression in triple-negative breast cancer using [64Cu]Cu-NOTA-Trodelvy-F(ab')2.

Purpose: The Trop2-targeting antibody-drug conjugate (ADC) sacituzumab govitecan (Trodelvy) has demonstrated remarkable efficacy in patients with metastatic triple-negative breast cancer (TNBC). ImmunoPET imaging offers a noninvasive method to visualize the expression and distribution of target anti...

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Bibliographic Details

Published in:	European Journal of Nuclear Medicine & Molecular Imaging Vol. 52; no. 9; pp. 3223 - 3238
Main Authors:	Huang, Wenpeng, Zhang, Yuwei, Xiao, Xiaoyan, Yang, Qi, Mixdorf, Jason C., Sun, Xinyao, Engle, Jonathan W., Fan, Yu, Li, Liming, Kang, Lei, Cai, Weibo
Format:	Journal Article
Published:	Springer Nature Jul2025
Online Access:	View this record in EBSCOhost