Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia.
In this study, the antioxidant capacity, the effect on anti-acetylcholinesterase and anti-urease enzyme inhibition, and kidney stone-reducing effects of different extracts from M.myrtifolia. In addition, the phytochemical content of the bioactive methanol extract was analyzed by HPLC-DAD. The methan...
| Publicado en: | International Journal of Environmental Health Research Vol. 35; no. 7; pp. 1833 - 1846 |
|---|---|
| Autores principales: | , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jul2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=186345435&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 186345435 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Jul2025 vid: 35 iid: 7 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 186345435 180059092 186345435 186345435 10.1080/09603123.2024.2409829 186345435 ppf: 1833 ppct: 13 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Phytochemical analysis and in vitro biological activity assessment of extracts from Micromeria myrtifolia. aug: au: T, Taskın M, Oksuz E, Rayaman M, Ermanoglu D, Taskın A.G, Acar Ö, Kılıç E, Çalışkan Salihi B, Yılmaz Nur Hk, Elçioğlu affil: Department of Pharmacognosy, Faculty of Pharmacy, Marmara University, Istanbul, Turkey sug: subj: Phytochemicals Analysis Plant Extracts Antioxidants Pharmacodynamics Antibiotics Pharmacodynamics Cholinesterase Inhibitors Pharmacodynamics Kidney Calculi Prevention and Control Methanol Chromatography, High Pressure Liquid Human In Vitro Studies Essential Oils Staphylococcus Aureus Comparative Studies Microbial Culture and Sensitivity Tests Funding Source ab: In this study, the antioxidant capacity, the effect on anti-acetylcholinesterase and anti-urease enzyme inhibition, and kidney stone-reducing effects of different extracts from M.myrtifolia. In addition, the phytochemical content of the bioactive methanol extract was analyzed by HPLC-DAD. The methanol extract showed strong DPPH (IC50:0.036 mg/mL) radical scavenging, Cu (II) ion (6.535 mmTroloxE) and Fe3+ (6.476 FeSO4) ion reducing antioxidant activity compared to other extracts. The methanol extract contained the highest amount of phenolic (400 mgGAE) and flavonoid (2.519 QuE) compounds. Moreover, the methanol extract had significant anticholinesterase (78.935%), anti-urease (71.014%) and calcium oxalate anti-crystallization (18.22%, 37.427%) activities. The findings show that all extracts exhibited varying amounts of antibacterial activity against Staphylococcus aureus. The bioactive methanol extract contained rosmarinic acid (31.35 µg), quercetin (12.99 µg) and chlorogenic acid (3.55 µg). The analyzed compounds are thought to contribute significantly to the pharmacological effect of the methanol extract. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|