Implementation Barriers and Facilitators in a Pilot Long-Acting HIV Treatment Intervention for Trans Women Living with HIV in San Francisco.

Little is known about long-acting HIV treatment implementation with trans women. We piloted and evaluated the implementation of novel strategies to increase uptake and use of long-acting HIV treatment among trans women in San Francisco. In 2022, qualitative formative nominal groups (n = 8) and in-de...

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Publicado en:AIDS Patient Care & STDs Vol. 39; no. 7; pp. 257 - 266
Autores principales: Wilson, Erin C., Myers, Janet, Muñoz Acosta, Geovanny, Sicro, Sofia, Schaeffer, Emily, Alleyne, Cat-Dancing, Diaz, Alfonso, Walker, Nicole, Vinson, Janie, Buchbinder, Susan, Scott, Hyman, Liu, Albert
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. Jul2025
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Implementation Barriers and Facilitators in a Pilot Long-Acting HIV Treatment Intervention for Trans Women Living with HIV in San Francisco.
      aug:
        au:
          Wilson, Erin C.
          Myers, Janet
          Muñoz Acosta, Geovanny
          Sicro, Sofia
          Schaeffer, Emily
          Alleyne, Cat-Dancing
          Diaz, Alfonso
          Walker, Nicole
          Vinson, Janie
          Buchbinder, Susan
          Scott, Hyman
          Liu, Albert
        affil: Center for Public Health Research, San Francisco Department of Public Health, San Francisco, California, USA.
      sug:
        subj:
          HIV Infections Drug Therapy
          HIV Infections Psychosocial Factors
          Anti-HIV Agents Administration and Dosage
          Trans Women Psychosocial Factors
          HIV-Positive Persons Psychosocial Factors
          Implementation Science
          Human
          Funding Source
          United States
          California
          Multimethod Studies
          Pilot Studies
          Descriptive Statistics
          Semi-Structured Interview
          Patient Compliance
          Anti-HIV Agents Adverse Effects
          Belonephobia
          Injections
          Transportation
          Incarceration
          Medical Mistrust
          Social Determinants of Health
          Drug Interactions
          Genetic Profile
          Eligibility Determination
          Rilpivirine Administration and Dosage
          Health Care Delivery
      ab: Little is known about long-acting HIV treatment implementation with trans women. We piloted and evaluated the implementation of novel strategies to increase uptake and use of long-acting HIV treatment among trans women in San Francisco. In 2022, qualitative formative nominal groups (n = 8) and in-depth interviews with providers (n = 11) were conducted to elicit facilitators and barriers to long-acting HIV treatment delivery among trans women living with HIV and to inform a pilot delivery model. Between August 2023 and August 2024, participants were enrolled into the program. Sequential mixed methods were used to evaluate formative and implementation data to understand barriers to starting long-acting treatment. Barriers for trans women were concerns about side effects, fear of needles, and difficulty adhering to bi-monthly injections. They were also concerned about missed injections from lack of transportation and incarceration and medical mistrust. Providers were most concerned with participant adherence due to social determinants (e.g., housing) and behavioral health challenges (e.g., methamphetamine use, mental health disorders). Buttock fillers and implants, patient worries about interactions with hormones, clinical barriers (e.g., availability of genotyping data), insurance, and managing prescriptions were also potential barriers. A significant barrier to implementation was the burden on referring clinic providers for eligibility screening and many trans women who were referred declined participation or were not eligible due to contraindicated clinical histories. Our study identified barriers to implementing long-acting HIV treatment among trans women living with HIV and provides novel implementation insights for clinics and interventions serving this community.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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