Capillary Blood Self‐Sampling for Therapeutic Drug Monitoring: A Mixed‐Methods Usability Study of the True Dose® Kit.

Objective: This study evaluates the usability in accordance with EN 62366 of the True Dose kit for capillary blood self‐sampling, to be used to analyze, specify, design, verify, and validate usability as it relates to the safety of medical devices focusing on user performance, experience, and user c...

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Publicado en:BioMed Research International Vol. 2025; pp. 1 - 10
Autores principales: Crafoord, Marie-Therése, Hedayati, Elham, Johnsson, Aina, Banerjee, Baisakhi
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 7/9/2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/9/2025
      vid: 2025
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/bmri/9973081
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        atl: Capillary Blood Self‐Sampling for Therapeutic Drug Monitoring: A Mixed‐Methods Usability Study of the True Dose® Kit.
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          Crafoord, Marie-Therése
          Hedayati, Elham
          Johnsson, Aina
          Banerjee, Baisakhi
        affil: Department of Clinical Science and Education,, Södersjukhuset (South Hospital),, Karolinska Institutet,, Stockholm, Sweden, ki.se
      sug:
        subj:
          Blood Specimen Collection
          Capillaries
          Self-Testing
          Drug Monitoring
          Reagent Kits, Diagnostic
          Product Evaluation
          Life Experiences
          Confidence
          Engineering
          User-Computer Interface
          Product Development
          Human
          Male
          Female
          Adult
          Middle Age
          Multimethod Studies
          Usability Study
          Criterion-Related Validity
          Quantitative Studies
          Qualitative Studies
          Convenience Sample
          Blood Volume
          Time Factors
          Questionnaires
          Scales
          Interviews
          Blood Chemical Analysis
          Drug Approval
          Clinical Trials
          Audiovisuals
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Objective: This study evaluates the usability in accordance with EN 62366 of the True Dose kit for capillary blood self‐sampling, to be used to analyze, specify, design, verify, and validate usability as it relates to the safety of medical devices focusing on user performance, experience, and user confidence through a mixed‐methods approach. The usability engineering process is needed to fulfill user interface design requirements as part of product development at True Dose kit. Methods: The study employed a convergent parallel design, integrating quantitative and qualitative data. Twenty‐five participants, recruited through convenience sampling, used the True Dose kit to perform capillary blood self‐sampling. Quantitative data were collected using three key performance metrics—collection of sufficient blood volume, absence of air bubbles, and duration of the self‐sampling process—along with two questionnaires, the System Usability Scale (SUS) and the Test Feedback Questionnaire (TFQ), to comprehensively assess user performance and experience. In contrast, qualitative data were obtained from interviews and free‐text responses. The integration of findings highlighted areas of convergence and divergence between the quantitative and qualitative data. Results: The overall SUS score was 82.70, indicating high usability. However, participants reported challenges with the complexity of instructions and stress associated with blood flow management. Qualitative insights revealed a preference for simplified visual guidance and highlighted the need for precise feedback mechanisms to ensure the correct execution of sampling steps. Despite these challenges, 92% of participants collected the required blood sample, with a median self‐sampling duration of 10.42 min. Conclusion: The True Dose kit demonstrates high usability potential, but improvements in instructional design and stress management are needed to enhance user experience and ensure consistent performance. Trial Registration: EUCT Number: 2024‐514818‐12‐00
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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