Experience-Driven Plasticity and the Emergence of Psychopathology: A Mechanistic Framework Integrating Development and the Environment Into the Research Domain Criteria (RDoC) Model.
Despite the clear importance of a developmental perspective for understanding the emergence of psychopathology across the life-course, such a perspective has yet to be integrated into the Research Domain Criteria (RDoC) model. In this paper, we articulate a framework that incorporates developmentall...
| Publicado en: | Journal of Psychopathology & Clinical Science Vol. 131; no. 6; pp. 575 - 588 |
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| Autores principales: | , |
| Formato: | Artículo |
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American Psychological Association
Aug2022
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=186597178&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 186597178 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 27697541 MXAZ jtl: Journal of Psychopathology & Clinical Science issn: 27697541 maglogo: N pubinfo: dt: Aug2022 vid: 131 iid: 6 pid: 34 pub: American Psychological Association artinfo: ui: 186597178 10.1037/abn0000598 ppf: 575 ppct: 13 formats: tig: atl: Experience-Driven Plasticity and the Emergence of Psychopathology: A Mechanistic Framework Integrating Development and the Environment Into the Research Domain Criteria (RDoC) Model. aug: au: McLaughlin, Katie A. Gabard-Durnam, Laurel affil: Department of Psychology, Harvard University Department of Psychology, Northeastern University Division of Developmental Medicine, Boston Children's Hospital su: Pathological psychology Individual differences Affect (Psychology) Structural frames Research & development sug: subj: Pathological psychology Individual differences Affect (Psychology) Framing Contractors Finish Carpentry Contractors Research and Development in Biotechnology Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology) Structural frames Research & development keyword: adversity development early life stress environment sensitive periods adversity development early life stress environment sensitive periods ab: Despite the clear importance of a developmental perspective for understanding the emergence of psychopathology across the life-course, such a perspective has yet to be integrated into the Research Domain Criteria (RDoC) model. In this paper, we articulate a framework that incorporates developmentally specific learning mechanisms that reflect experience-driven plasticity as additional units of analysis in the existing RDoC matrix. These include both experience-expectant learning mechanisms that occur during sensitive periods of development and experience-dependent learning mechanisms that may exhibit substantial variation across development. Incorporating these learning mechanisms allows for clear integration not only of development but also environmental experience into the RDoC model. We demonstrate how individual differences in environmental experiences—such as early life adversity—can be leveraged to identify experience-driven plasticity patterns across development and apply this framework to consider how environmental experience shapes key biobehavioral processes that comprise the RDoC model. This framework provides a structure for understanding how affective, cognitive, social, and neurobiological processes are shaped by experience across development and ultimately contribute to the emergence of psychopathology. We demonstrate how incorporating an experience-driven plasticity framework is critical for understanding the development of many processes subsumed within the RDoC model, which will contribute to greater understanding of developmental variation in the etiology of psychopathology and can be leveraged to identify potential windows of heightened developmental plasticity when clinical interventions might be maximally efficacious. General Scientific Summary: We present a framework that incorporates developmentally specific learning mechanisms that reflect experience-driven plasticity as additional units of analysis in the Research Domain Criteria (RDoC) matrix. Incorporating these learning mechanisms allows for both development and environmental experience to be integrated into the RDoC model. This experience-driven plasticity framework can stimulate progress in understanding the development of many processes subsumed within the RDoC model, contribute to greater understanding of developmental variation in the onset of psychopathology, and can be leveraged to identify developmental windows of heightened plasticity when clinical interventions might be maximally efficacious. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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