Inter-reader reliability of Ovarian-Adnexal Reporting and Data System US: a systematic review and meta-analysis.

Purpose: Ovarian-Adnexal Reporting and Data System (O-RADS) US provides a standardized lexicon for ovarian and adnexal lesions, facilitating risk stratification based on morphological features for malignancy assessment, which is essential for proper management. However, systematic determination of i...

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Publicado en:Abdominal Radiology Vol. 50; no. 8; pp. 3806 - 3816
Autores principales: Bae, Sang Min, Kim, Dong Hwan, Kang, Ji Hun
Formato: Journal Article
Publicado: Springer Nature Aug2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
      vid: 50
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00261-025-04813-2
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        atl: Inter-reader reliability of Ovarian-Adnexal Reporting and Data System US: a systematic review and meta-analysis.
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          Bae, Sang Min
          Kim, Dong Hwan
          Kang, Ji Hun
        affil: https://ror.org/02f9avj37 Hanyang University Guri Hospital, Guri-si, Korea, Republic of
      sug:
      ab: Purpose: Ovarian-Adnexal Reporting and Data System (O-RADS) US provides a standardized lexicon for ovarian and adnexal lesions, facilitating risk stratification based on morphological features for malignancy assessment, which is essential for proper management. However, systematic determination of inter-reader reliability in O-RADS US categorization remains unexplored. This study aimed to systematically determine the inter-reader reliability of O-RADS US categorization and identify the factors that affect it. Methods: Original articles reporting the inter-reader reliability of O-RADS US in lesion categorization were identified in the MEDLINE, EMBASE, and Web of Science databases from January 2018 to December 2023. DerSimonian-Laird random-effects models were used to determine the meta-analytic pooled inter-reader reliability of the O-RADS US categorization. Subgroup meta-regression analysis was performed to identify the factors causing study heterogeneity. Results: Fourteen original articles with 5139 ovarian and adnexal lesions were included. The inter-reader reliability of O-RADS US in lesion categorization ranged from 0.71 to 0.99, with a meta-analytic pooled estimate of 0.83 (95% CI, 0.78–0.88), indicating almost perfect reliability. Substantial study heterogeneity was observed in the inter-reader reliability of the O-RADS US categorization (I2 = 96.9). In subgroup meta-regression analysis, reader experience was the only factor associated with study heterogeneity. Pooled inter-reader reliability of the O-RADS US categorization was higher in studies with all experienced readers (0.86; 95% CI, 0.81–0.91) compared to those with multiple readers including trainees (0.74; 95% CI, 0.70–0.78; P = 0.009). The inter-reader reliability of US descriptors ranged from 0.39 to 0.97, with ascites and peritoneal nodules showing almost perfect reliability (0.79− 0.97). Conclusion: The O-RADS US risk stratification system demonstrated almost perfect inter-reader reliability in lesion categorization. Our results highlight the importance of targeted training and descriptor simplification to improve inter-reader reliability and clinical adoption.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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