Intracellular enhancement technique for gadoxetic acid-enhanced hepatobiliary-phase magnetic resonance imaging: evaluation of hepatic function.

Purpose: To investigate the utility of intracellular enhancement (ICE) technique which suppresses signals from the extracellular space for the evaluation of hepatic function on gadoxetic acid-enhanced hepatobiliary-phase (HBP) images. Methods: We subjected 67 patients with suspected neoplastic hepat...

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Publicado en:Abdominal Radiology Vol. 50; no. 8; pp. 3506 - 3516
Autores principales: Fonseca, Dara, Nakamura, Yuko, Higaki, Toru, Maeda, Shogo, Nishihara, Takashi, Bito, Yoshitaka, Takizawa, Masahiro, Kondo, Shota, Higashino, Ryo, Morishita, Shintaro, Akiyama, Yuji, Fukuma, Shingo, Kawaoka, Tomokazu, Tsuge, Masataka, Oka, Shiro, Awai, Kazuo
Formato: Journal Article
Publicado: Springer Nature Aug2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
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      pub: Springer Nature
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        atl: Intracellular enhancement technique for gadoxetic acid-enhanced hepatobiliary-phase magnetic resonance imaging: evaluation of hepatic function.
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          Fonseca, Dara
          Nakamura, Yuko
          Higaki, Toru
          Maeda, Shogo
          Nishihara, Takashi
          Bito, Yoshitaka
          Takizawa, Masahiro
          Kondo, Shota
          Higashino, Ryo
          Morishita, Shintaro
          Akiyama, Yuji
          Fukuma, Shingo
          Kawaoka, Tomokazu
          Tsuge, Masataka
          Oka, Shiro
          Awai, Kazuo
        affil: https://ror.org/03t78wx29 Hiroshima University, Hiroshima City, Japan
      sug:
      ab: Purpose: To investigate the utility of intracellular enhancement (ICE) technique which suppresses signals from the extracellular space for the evaluation of hepatic function on gadoxetic acid-enhanced hepatobiliary-phase (HBP) images. Methods: We subjected 67 patients with suspected neoplastic hepatic lesions to gadoxetic acid-enhanced HBP imaging with and without ICE [i-HBP, conventional-HBP (c-HBP)]. A radiologist calculated the liver/spleen contrast (LSC) [LSC = signal intensity (SI) of liver/SI of spleen]. Receiver-operating analysis was used to evaluate the diagnostic value of the LSC on i-HBP- (i-LSC) and c-HBP images (c-LSC) to differentiate between Child-Pugh classes A and B. Results: Of the 67 patients, 57 were in Child-Pugh class A and 10 were in class B. For their differentiation, the area under the curve value of i-LSC was higher than of c-LSC (0.81 vs. 0.68). Conclusions: ICE technique can improve the accuracy of estimating hepatic function on HBP images.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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