Patient and public involvement in lifestyle randomized controlled trials: a systematic review.

Background: Motivating patients to take part in randomized controlled trials (RCTs) is challenging. Patient and public involvement (PPI), recommended for reporting since 2011, may potentially improve the recruitment and retention of participants in research. Aim: In this systematic review we aimed t...

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Publicado en:Journal of Public Health: From Theory to Practice (2198-1833) Vol. 33; no. 8; pp. 1713 - 1726
Autores principales: Bouzalmate-Hajjaj, Amira, Cano-Ibáñez, Naomi, Khan, Khalid Saeed, Bueno-Cavanillas, Aurora, Guijarro, Paloma Massó
Formato: Artículo
Publicado: Springer Nature Aug2025
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Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
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      pub: Springer Nature
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        186838153
        10.1007/s10389-023-02148-0
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        atl: Patient and public involvement in lifestyle randomized controlled trials: a systematic review.
      aug:
        au:
          Bouzalmate-Hajjaj, Amira
          Cano-Ibáñez, Naomi
          Khan, Khalid Saeed
          Bueno-Cavanillas, Aurora
          Guijarro, Paloma Massó
        affil:
          https://ror.org/04njjy449 Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Granada, Campus de la Salud. Avda. de la Investigación 11, 18016, Granada, Spain
          https://ror.org/02f01mz90 Preventive Medicine Unit. Universitary Hospital Virgen de las Nieves, Granada, Spain
          https://ror.org/050q0kv47 CIBER de Epidemiología y Salud Pública (CIBERESP-Spain), Madrid, Spain
          https://ror.org/026yy9j15 Instituto de Investigación Biosanitaria de Granada (IBS.GRANADA), Granada, Spain
      su:
        Lifestyles
        Human research subjects
        Randomized controlled trials
        Patient participation
        Obesity
        Adults
        Patient selection
        Research funding
        Mann Whitney U Test
        Systematic reviews
        MEDLINE
        Metabolic syndrome
        Medical databases
        Data analysis software
        Confidence intervals
      sug:
        subj:
          Lifestyles
          Human research subjects
          Randomized controlled trials
          Patient participation
          Obesity
          Adults
          Patient selection
          Research funding
          Mann Whitney U Test
          Systematic reviews
          MEDLINE
          Metabolic syndrome
          Medical databases
          Data analysis software
          Confidence intervals
      keyword:
        Lifestyle
        Patient and public involvement
        Lifestyle
        Patient and public involvement
      ab: Background: Motivating patients to take part in randomized controlled trials (RCTs) is challenging. Patient and public involvement (PPI), recommended for reporting since 2011, may potentially improve the recruitment and retention of participants in research. Aim: In this systematic review we aimed to identify the extent of PPI reported in RCTs of lifestyle interventions amongst adults and its impact on enrolment and retention rates. Methods: After prospective registration in PROSPERO (CRD42022359833), we searched the MEDLINE, Scopus, Web of Science, and Cochrane Library databases from inception to December 2022. We included RCTs with dietary interventions, with or without physical activity, and with or without behavioural support, among adults with overweight, obesity, or metabolic syndrome. Data extraction and study quality assessment were performed independently by two reviewers. Results: Of 1063 records, 26 RCTs (12,100 participants) were included. Among these, 22 were published after 2011. Of the total, 17 (65%) RCTs mentioned PPI directly (two studies) or indirectly. The methodological quality was high in 13 studies (50%), with no significant differences in PPI (p-value = 0.3187). The enrolment rate was no different but the median retention rate was high among RCTs with PPI (0.90; 95% CI 0.86–0.95) compared to those without (0.83; 95% CI 0.70–0.87) (p-value = 0.0426). Conclusion: PPI improved the retention of participants in RCTs with lifestyle interventions. However, its impact on enrolment was not clear. Overall, PPI should be encouraged in the RCT research process.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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