Low Voltage Area Modification in Older Patients With Atrial Fibrillation.
Background: Age has been found as an important factor affecting the low voltage area (LVA) in patients with atrial fibrillation (AF). This study aims to investigate the potential benefit of LVA modification in older AF patients. Methods: This study constitutes a sub‐analysis of the STABLE‐SR‐II and...
| Publicado en: | Pacing & Clinical Electrophysiology Vol. 48; no. 7; pp. 665 - 672 |
|---|---|
| Autores principales: | , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jul2025
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=186991069&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 186991069 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01478389 4F8 jtl: Pacing & Clinical Electrophysiology issn: 01478389 maglogo: Y pubinfo: dt: Jul2025 vid: 48 iid: 7 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 186991069 185335435 186991069 186991069 10.1111/pace.15203 186991069 ppf: 665 ppct: 7 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Low Voltage Area Modification in Older Patients With Atrial Fibrillation. aug: au: Chen, Ning Xu, Zhou Chen, Hongwu Yang, Gang Wang, Lei Shen, Youmei Wu, Nan Ju, Sion Ju, Weizhu Li, Mingfang Gu, Kai Liu, Hailei Chen, Minglong affil: The First Affiliated Hospital of Nanjing Medical University, Nanjing, China sug: subj: Atrial Fibrillation Physiopathology Atrial Fibrillation Surgery Electrophysiology Pulmonary Veins Surgery Catheter Ablation Methods Treatment Outcomes Human Male Female Aged Aged, 80 and Over Cardiac Patients Comparative Studies Tachycardia, Atrial Prevention and Control Recurrence Risk Factors Descriptive Statistics Confidence Intervals Cox Proportional Hazards Model Aged: 65+ years Aged, 80 & over Male Female ab: Background: Age has been found as an important factor affecting the low voltage area (LVA) in patients with atrial fibrillation (AF). This study aims to investigate the potential benefit of LVA modification in older AF patients. Methods: This study constitutes a sub‐analysis of the STABLE‐SR‐II and STABLE‐SR‐III trials, wherein patients with persistent AF (PeAF) or paroxysmal AF (PAF) were randomized to undergo either circumferential pulmonary vein isolation (CPVI) alone or additional LVA modification. Patients aged ≥65 years were analyzed. The primary outcome was freedom from atrial tachyarrhythmias (ATAs). Results: A total of 510 patients (mean age 70.2 ± 3.8 years, 264 male) were analyzed, comprising 96 PeAF and 414 PAF patients. Among patients without LVA, the risk of ATAs recurrence was similar between PeAF and PAF patients in the propensity score‐matched model (adjusted HR, 1.49 [0.54–4.33]; p = 0.431). Both PeAF (adjusted HR, 0.35 [95% CI, 0.12–0.98]; p = 0.048) and PAF patients (adjusted HR, 0.41 [0.19–0.81]; p = 0.013) could benefit from additional LVA modification in the Cox proportional hazards model. Conclusions: In older patients with AF, the recurrence rate following CPVI alone is comparable between those with PAF and PeAF in the absence of LVA. However, the presence of LVA is associated with higher recurrence rates in both PAF and PeAF patients, while additional LVA modification effectively reduces recurrence irrespective of AF type. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|