Flexible Distributed Lag Models for Count Data Using mgcv.

In this tutorial we present the use of R package mgcv to implement Distributed Lag Non-Linear Models (DLNMs) in a flexible way. Interpretation of smoothing splines as random quantities enables approximate Bayesian inference, which in turn allows uncertainty quantification and comprehensive model che...

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Publicado en:American Statistician Vol. 79; no. 3; pp. 371 - 383
Autores principales: Economou, Theo, Parliari, Daphne, Tobias, Aurelio, Dawkins, Laura, Steptoe, Hamish, Sarran, Christophe, Stoner, Oliver, Lowe, Rachel, Lelieveld, Jos
Formato: Artículo
Publicado: Taylor & Francis Ltd Aug2025
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
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        10.1080/00031305.2025.2505514
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        atl: Flexible Distributed Lag Models for Count Data Using mgcv.
      aug:
        au:
          Economou, Theo
          Parliari, Daphne
          Tobias, Aurelio
          Dawkins, Laura
          Steptoe, Hamish
          Sarran, Christophe
          Stoner, Oliver
          Lowe, Rachel
          Lelieveld, Jos
        affil:
          Department of Mathematics and Statistics, University of Exeter, Exeter, UK
          Climate and Atmosphere Research, The Cyprus Institute, Nicosia, Cyprus
          Laboratory of Atmospheric Physics, Aristotle University of Thessaloniki, Thessaloniki, Greece
          Institute for Environmental Assessment and Water Research, Spanish National Research Council, Barcelona, Spain
          Met Office, Exeter, UK
          School of Mathematics and Statistics, University of Glasgow, Glasgow, UK
          Barcelona Supercomputing Center (BSC), Barcelona, Spain
          Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain
          London School of Hygiene & Tropical Medicine, London, UK
          Max Planck Institute for Chemistry, Mainz, Germany
      su:
        Epidemiology
        Statistical models
        Spatial variation
        Mixture distributions (Probability theory)
        Bayesian analysis
      sug:
        subj:
          Epidemiology
          Statistical models
          Spatial variation
          Mixture distributions (Probability theory)
          Bayesian analysis
      keyword:
        Bayesian inference
        DLNM
        Environmental epidemiology
        Heat-stress
        Penalized splines
        Bayesian inference
        DLNM
        Environmental epidemiology
        Heat-stress
        Penalized splines
      ab: In this tutorial we present the use of R package mgcv to implement Distributed Lag Non-Linear Models (DLNMs) in a flexible way. Interpretation of smoothing splines as random quantities enables approximate Bayesian inference, which in turn allows uncertainty quantification and comprehensive model checking. We illustrate various modeling situations using open-access epidemiological data in conjunction with simulation experiments. We demonstrate the inclusion of temporal structures and the use of mixture distributions to allow for extreme outliers. Moreover, we demonstrate interactions of the temporal lagged structures with other covariates with different lagged periods for different covariates. Spatial structures are also demonstrated, including smooth spatial variability and Markov random fields, in addition to hierarchical formulations to allow for non-structured dependency. Posterior predictive simulation is used to ensure models verify well against the data.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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