Effects of Exercise on Muscle Strength and VO2 Peak in Patients with Pulmonary Hypertension: A Systematic Review and Meta-Analysis.

Exercise programs are one of the treatments used to extend the life expectancy of individuals with pulmonary hypertension; however, there is conflicting evidence regarding how well exercise increases muscle strength and VO2 peak. Six databases and one other source were used in a comprehensive search...

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Publicado en:Pacific Rim International Journal of Nursing Research Vol. 29; no. 2; pp. 306 - 326
Autores principales: Andreas Rantepadang, Angelia Friska Tendean, Ellen Padaunan, I. Gede Purnawinadi, Silvia Dewi Mayasari Riu, Denny Maurits Ruku
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Thailand Nursing & Midwifery Council Apr-Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr-Jun2025
      vid: 29
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      pub: Thailand Nursing & Midwifery Council
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        10.60099/prijnr.2025.271912
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        atl: Effects of Exercise on Muscle Strength and VO2 Peak in Patients with Pulmonary Hypertension: A Systematic Review and Meta-Analysis.
      aug:
        au:
          Andreas Rantepadang
          Angelia Friska Tendean
          Ellen Padaunan
          I. Gede Purnawinadi
          Silvia Dewi Mayasari Riu
          Denny Maurits Ruku
        affil: Faculty of Nursing, Klabat University, Manado-Indonesia
      sug:
        subj:
          Hypertension, Pulmonary Rehabilitation
          Rehabilitation, Pulmonary
          Therapeutic Exercise
          Muscle Strength Evaluation
          Oxygen Consumption Evaluation
          Exercise Tolerance Evaluation
          Quality of Life Evaluation
          Therapeutic Exercise Adverse Effects
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Systematic Review
          Meta Analysis
          Embase
          CINAHL Database
          Medline
          Cochrane Library
          PubMed
          Peak Expiratory Flow Rate
          Checklists
          Descriptive Statistics
          Data Analysis Software
          Chi Square Test
          Inferential Statistics
          Gait Analysis
          Oxygen Saturation
          Cardiac Output
          Social Participation
          Mental Health
          Clinical Assessment Tools
          Program Evaluation
          Program Implementation
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Exercise programs are one of the treatments used to extend the life expectancy of individuals with pulmonary hypertension; however, there is conflicting evidence regarding how well exercise increases muscle strength and VO2 peak. Six databases and one other source were used in a comprehensive search conducted from June to August 2024 to find relevant research published in English between 2006 and 2022. The standard mean difference, mean difference, and risk difference with a 95% confidence interval were used to determine the effect of exercise. Biased publications were presented with a risk of bias summary/graph. Employing the Critical Appraisal Skills Program, all reviewers independently assessed the methodological quality of the included studies and extracted data. The results showed 13 randomized control trial studies with 421 respondents, consisting of 204 and 217 in the intervention and control groups, respectively. Exercise had significant effects on improving muscle strength, VO2 peak (primary outcomes), oxygen saturation, cardiac output, six-minute walk test, and several aspects of health-related quality of life as assessed by the SF-36 questionnaire (secondary outcomes), and there were no serious adverse events linked to exercise. However, exercise did not significantly alter VE/VCO2 slope, cardiac index, role physical, vitality, mental health, physical component summary, or mental component summary between the intervention than control groups among people with pulmonary hypertension. In conclusion, an exercise program of supervised may improve VO2 peak and muscle strength and does not result in an increased risk of serious adverse events. Nonetheless, individuals with severe conditions of pulmonary hypertension should be carefully considered when doing exercise programs.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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