Development of a Program to Optimize the Experience and the Use of At-Home Oral Chemotherapies in Pediatric Acute Lymphoblastic Leukemia: A Participatory Approach Using the Behavior Change Wheel.

Background: Children diagnosed with acute lymphoblastic leukemia (ALL) receive oral chemotherapies (OCs) for 2 years. The at-home self-management of OCs and their consequences on the child lead to multifaceted difficulties that can impact their optimal use and the family's well-being. We report the...

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Publicado en:Journal of Pediatric Hematology/Oncology Nursing Vol. 42; no. 3; pp. 85 - 100
Autores principales: Labbé, Angéline, Guillaumie, Laurence, D'Avignon, Marianne Olivier, David, Pierre-Marie, Lauzier, Sophie, Laverdière, Isabelle
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. May/Jun2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May/Jun2025
      vid: 42
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Development of a Program to Optimize the Experience and the Use of At-Home Oral Chemotherapies in Pediatric Acute Lymphoblastic Leukemia: A Participatory Approach Using the Behavior Change Wheel.
      aug:
        au:
          Labbé, Angéline
          Guillaumie, Laurence
          D'Avignon, Marianne Olivier
          David, Pierre-Marie
          Lauzier, Sophie
          Laverdière, Isabelle
        affil: Faculty of Pharmacy, Université Laval, Québec, QC, Canada
      sug:
        subj:
          Leukemia, Lymphocytic, Acute Psychosocial Factors
          Leukemia, Lymphocytic, Acute Drug Therapy
          Chemotherapy, Cancer
          Antineoplastic Agents Administration and Dosage
          Administration, Oral
          Home Health Care
          Family Support
          Implementation Science
          Program Development
          Treatment Outcomes
          Human
          Funding Source
          Canada
          Male
          Female
          Child, Preschool
          Child
          Parents
          Behavioral Changes
          Health Services Research
          Conceptual Framework
          Action Research
          Attitude to Change
          Research Personnel
          Health Personnel
          Meetings
          Collaboration
          Psychological Well-Being
          Descriptive Statistics
          Patient Education
          Patient Safety
          Counseling
          Antineoplastic Agents Adverse Effects
          Empowerment
          Self-Management
          Family Education
          Academic Medical Centers
          Pediatric Oncology Nursing
          Medication Compliance
          Goodness of Fit Chi Square Test
          Thematic Analysis
          Support, Social
          Health Knowledge
          Child, Preschool: 2-5 years
          Child: 6-12 years
          Male
          Female
      ab: Background: Children diagnosed with acute lymphoblastic leukemia (ALL) receive oral chemotherapies (OCs) for 2 years. The at-home self-management of OCs and their consequences on the child lead to multifaceted difficulties that can impact their optimal use and the family's well-being. We report the development process and the detailed plan of a program to support families throughout the treatment. Method: The development combined a participatory approach with the three stages of Behavior Change Wheel (BCW) framework, namely understanding the behavior to change, identifying intervention options, and identifying content and implementation options. A working group (i.e., researchers, parents, and professionals involved in the care of children with ALL) participated at all development stages through online meetings and co-construction activities. Results: The core objective targeted by the program was defined as: to enable families to face the difficulties met with OC by mobilizing tools and resources in collaboration with the healthcare team to support the proper use of OC and the family well-being. The program plan comprises three components with various interventions dispensed at key times during treatment: education and training for OC management and safe use, evaluation and counseling about OC side effects, and empowerment of families and normalization of their experience with OC. Discussion: The combination of a participatory approach and a structured framework for the program development is likely to increase its relevance, acceptability, and efficacy. This program has the potential to support more effective and safe use of OC, as well as the well-being of the child and their family.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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