| Sumario: | This study to examine associations between cardiorespiratory fitness (CRF), 24-hour movement components, and cardiometabolic risk factors in children from southern Brazil, emphasizing the critical variables in these relationships. The sample included 186 schoolchildren (6–11 years, 8.57±1.56). Waist circumference (WC) and CRF were assessed using PROESP-Br protocols, while physical activity (moderate to vigorous – MVPA, and light – LPA) was measured via accelerometers. Sleep and screen time were reported by parents, and fasting blood samples provided data on triglycerides, HDL cholesterol, glucose, insulin, and HOMA-IR. Network analysis highlight WC, systolic blood pressure, and MVPA as central variables with significant connectivity. MVPA emerged as central among 24-hour movement behaviors, with CRF playing an intermediary role. Results underscore WC and MVPA's relationship on cardiometabolic health, supporting interventions targeting MVPA to prevent early cardiometabolic risks in children.
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