Task Practice With and Without Aerobic Exercise Improves Health-related Quality of Life and Social Participation Post-stroke: A Randomized Clinical Trial.

Background: Physical, cognitive, and psychosocial impairments experienced by individuals post-stroke detrimentally impact health-related quality of life (HRQoL). Rehabilitation interventions targeting the recovery of motor function aim to improve community reintegration and HRQoL. Aerobic exercise h...

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Publicado en:Neurorehabilitation & Neural Repair Vol. 39; no. 8; pp. 591 - 602
Autores principales: Linder, Susan M., Bischof-Bockbrader, Andrea, Ince Hocaoglu, Ozlenen Eylul, Bethoux, Francois, Davidson, Sara, Harris, Donayja, Li, Yadi, Lapin, Brittany, Alberts, Jay L.
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Sage Publications Inc. Aug2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Aug2025
      vid: 39
      iid: 8
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Task Practice With and Without Aerobic Exercise Improves Health-related Quality of Life and Social Participation Post-stroke: A Randomized Clinical Trial.
      aug:
        au:
          Linder, Susan M.
          Bischof-Bockbrader, Andrea
          Ince Hocaoglu, Ozlenen Eylul
          Bethoux, Francois
          Davidson, Sara
          Harris, Donayja
          Li, Yadi
          Lapin, Brittany
          Alberts, Jay L.
        affil: Cleveland Clinic, Department of Physical Medicine and Rehabilitation, Cleveland, OH, USA
      sug:
        subj:
          Aerobic Exercises
          Quality of Life Evaluation
          Affect Evaluation
          Social Participation Evaluation
          Stroke Rehabilitation
          Upper Extremity Physiology
          Task Performance and Analysis
          Ohio
          Funding Source
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Randomized Controlled Trials
          Random Assignment
          Pretest-Posttest Control Group Design
          Questionnaires
          Self Report
          Activities of Daily Living
          Physical Mobility
          Hand Physiology
          Recovery
          Chi Square Test
          Fisher's Exact Test
          Data Analysis Software
          Descriptive Statistics
          Scales
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Physical, cognitive, and psychosocial impairments experienced by individuals post-stroke detrimentally impact health-related quality of life (HRQoL). Rehabilitation interventions targeting the recovery of motor function aim to improve community reintegration and HRQoL. Aerobic exercise has also been shown to have global effects in individuals post-stroke, positively affecting motor and mood-related outcomes. Objective: To determine the effects of forced-rate aerobic exercise (FE) coupled with upper extremity repetitive task practice (RTP) on HRQoL and mood in individuals post-stroke. Methods: A rater blinded randomized clinical trial was conducted. Individuals ≥6 months post-stroke received 90-minute sessions of FE+RTP or time-matched RTP alone, 3×/week for 8 weeks. The Stroke Impact Scale (SIS), Patient-Reported Outcomes Measurement Information System (PROMIS-29), and Centers For Epidemiology Studies-Depression Scale (CES-D) were administered at baseline, end of treatment (EOT), EOT+6 months, and EOT+12 months. Results: Sixty participants enrolled in the study and 57 completed the self-reported questionnaires (FE + RTP, N = 29; RTP alone, N = 28). Both groups improved significantly at each time point in the following SIS domains: physical problems, feelings, activities of daily living, mobility, hand use, meaningful activities, and overall recovery; and in the participation domain of PROMIS-29. Depressive symptomology as measured by CES-D improved from baseline to EOT+6. There were no significant group differences in any of the outcomes. Conclusions: Both interventions were comparably effective in improving HRQoL despite the FE+RTP group receiving only half the dose of RTP compared to the control group (RTP only). Improvements were maintained up to 1 year post-intervention.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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