Reactivation fails to offer the improvement sleep does.

In a dynamic process that ultimately affords memories their persistence, memory reconsolidation can serve to strengthen associations following reactivation, particularly in sleep, where active processes may effect overnight enhancement. Reactivation can also occur in wake, where improvement would be...

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Publicado en:Sleep Advances Vol. 6; no. 2; pp. 1 - 10
Autores principales: Barsky, Murray M, Morgan, Alexandra, Stickgold, Robert
Formato: pictorial poetry research tables/charts Journal Article
Publicado: Oxford University Press / USA Apr2025
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2025
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      pub: Oxford University Press / USA
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        187147208
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        10.1093/sleepadvances/zpaf035
        187147208
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        atl: Reactivation fails to offer the improvement sleep does.
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        au:
          Barsky, Murray M
          Morgan, Alexandra
          Stickgold, Robert
        affil: Harvard University, Cambridge, MA 02138 USA
      sug:
        subj:
          Wakefulness Physiology
          Sleep Physiology
          Neuronal Plasticity Physiology
          Memory Evaluation
          Paradigms
          Task Performance and Analysis
          Circadian Rhythm
          Sleep, REM Physiology
          Human
          Funding Source
          Learning Methods
          Cognition
          Psychomotor Performance
          Students, College
          Male
          Female
          Adolescence
          Adult
          Descriptive Statistics
          One-Way Analysis of Variance
          Unpaired T-Tests
          Data Analysis Software
          Post Hoc Analysis
          Adolescent: 13-18 years
          Adult: 19-44 years
          Male
          Female
      ab: In a dynamic process that ultimately affords memories their persistence, memory reconsolidation can serve to strengthen associations following reactivation, particularly in sleep, where active processes may effect overnight enhancement. Reactivation can also occur in wake, where improvement would be unexpected. In an earlier study using performance on the Weather Prediction Task (WPT) as a measure of probabilistic category learning, we looked at the effect of sleep and found significant improvement after a daytime nap, where improvement correlated with the amount of REM sleep obtained. When we introduced interference training following sleep, this REM sleep benefit vanished: post-learning task memory was otherwise preserved. Here, we follow up on these results and test whether reactivation itself—wake reactivation—might be sufficient to induce the improvement found after REM sleep. Our results show that it is not: we saw no improvement on the WPT following reactivation in wake, suggesting sleep may be unique in supporting memory improvement. When we looked at interference effects, we saw unexplained differences between wake and sleep that suggest that while interference is uniformly destabilizing of WPT memories during wake, interference after REM show effects on the memory trace formed during initial learning that are distinctly different from its effects on the subsequently sleep-enhanced memory.
      pubtype: Academic Journal
      doctype:
        pictorial
        poetry
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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